Czech Honeydew Honeys-A Potential Source of Local Medical Honey with Strong Antimicrobial Activity

Overview

Journal Pharmaceuticals (Basel)

Publisher MDPI

Specialty Chemistry

Date 2024 Jul 27

PMID 39065691

Authors

Ludovit Pudelka

Radek Sleha

Sylva Janovska

Vera Radochova

Pavel Bostik

Affiliations

Soon will be listed here.

Abstract

An increasing resistance of microbes to antibiotics, the emergence of multidrug-resistant and extremely resistant strains, and the long time needed to develop new antibiotics are driving the search for additional sources of antibacterial agents. The aim of the study was to compare the efficacy of Czech honeys with already available pharmaceutical agents containing medicinal honey, and to perform basic biochemical analysis of Czech samples, including detection of undesirable chemical substances. The results showed strong antibacterial activity of Czech honeydew honeys compared to the control group, especially against G+ pathogens, with an average MIC of 9.44% compared to 17.54%, and comparable activity against G- of 16.48% versus 16.66%. In addition to the strong antibacterial activity, this study confirmed the safety and quality of Czech honeys and helped to select the character of a possible source for in vivo testing and subsequent clinical trials.

Citing Articles

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Grabek-Lejko D, Milek M, Dzugan M Sci Rep. 2024; 14(1):31170.

PMID: 39732871 PMC: 11682447. DOI: 10.1038/s41598-024-82429-0.

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