First Report on the Occurrence and Antibiotic Resistance Profile of Colistin-Resistant in Raw Beef and Cow Feces in Vietnam

Overview

Journal Microorganisms

Specialty Microbiology

Date 2024 Jul 27

PMID 39065073

Authors

Hoang Minh Duc

Tran Thi Khanh Hoa

Nguyen Van Thang

Hoang Minh Son

Affiliations

Soon will be listed here.

Abstract

Colistin-resistant (COE) has been recently recognized as a serious threat to animal and human health. This study aimed to determine the prevalence and antibiotic resistance profile of COE isolated from raw beef and cow feces in Vietnam. Our results showed that 16% (16/100) and 32% (32/100) of raw beef and cow feces samples were positive for COE, respectively. A total of 48 COE strains were isolated, with 16 originating from raw beef and 32 from cow feces samples. The antibiotic susceptibility test revealed that the COE isolates were highly resistant to ampicillin, tetracycline, florfenicol, trimethoprim/sulfamethoxazole, streptomycin, and nalidixic acid, with resistance rates ranging from 66.67% to 87.5%. In addition, 87.5% of the isolates were identified to be multidrug-resistant strains. Further molecular characterization indicated that all COE isolates carried the gene, with 16 of them also harboring genes. Taken together, the findings in this study demonstrate that raw beef and cow feces are important sources of COE, which can be potentially transmitted to humans through the food chain.

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