The Role of Gut Microbiome in Sleep Quality and Health: Dietary Strategies for Microbiota Support
Overview
Affiliations
Dietary components, including dietary fiber, unsaturated fatty acids, and polyphenols, along with meal timing and spacing, significantly affect the microbiota's capacity to produce various metabolites essential for quality sleep and overall health. This review explores the role of gut microbiota in regulating sleep through various metabolites such as short-chain fatty acids, tryptophan, serotonin, melatonin, and gamma-aminobutyric acid. A balanced diet rich in plant-based foods enhances the production of these sleep-regulating metabolites, potentially benefiting overall health. This review aims to investigate how dietary habits affect gut microbiota composition, the metabolites it produces, and the subsequent impact on sleep quality and related health conditions.
Seol J, Iwagami M, Kayamare M, Yanagisawa M J Med Internet Res. 2025; 27:e64749.
PMID: 39883933 PMC: 11826953. DOI: 10.2196/64749.
The Effect of Sleep Disruption on Cardiometabolic Health.
Hong S, Lee D, Yoon D, Yoo S, Kim J Life (Basel). 2025; 15(1).
PMID: 39860000 PMC: 11766988. DOI: 10.3390/life15010060.
Moreno-Altamirano L, Robles-Rivera K, Castelan-Sanchez H, Vaca-Paniagua F, Inarritu Perez M, Hernandez-Valencia S Nutrients. 2024; 16(23).
PMID: 39683634 PMC: 11644225. DOI: 10.3390/nu16234241.
Sejbuk M, Mironczuk-Chodakowska I, Karav S, Witkowska A Antioxidants (Basel). 2024; 13(10).
PMID: 39456473 PMC: 11505337. DOI: 10.3390/antiox13101220.
The Hidden Dangers of Sedentary Living: Insights into Molecular, Cellular, and Systemic Mechanisms.
Guerreiro Diniz D, Bento-Torres J, da Costa V, Carvalho J, Tomas A, Galdino de Oliveira T Int J Mol Sci. 2024; 25(19).
PMID: 39409085 PMC: 11476792. DOI: 10.3390/ijms251910757.