Implications of LncRNAs in -associated Gastrointestinal Cancers: Underlying Mechanisms and Future Perspectives

Overview

Journal Front Cell Infect Microbiol

Specialties Cell Biology
Infectious Diseases
Microbiology

Date 2024 Jul 22

PMID 39035354

Authors

Lei Zhang

Fei Yu

Yue Zhang

Peifeng Li

Affiliations

Soon will be listed here.

Abstract

() is a harmful bacterium that is difficult to conveniently diagnose and effectively eradicate. Chronic infection increases the risk of gastrointestinal diseases, even cancers. Despite the known findings, more underlying mechanisms are to be deeply explored to facilitate the development of novel prevention and treatment strategies of infection. Long noncoding RNAs (lncRNAs) are RNAs with more than 200 nucleotides. They may be implicated in cell proliferation, inflammation and many other signaling pathways of gastrointestinal cancer progression. The dynamic expression of lncRNAs indicates their potential to be diagnostic or prognostic biomarkers. In this paper, we comprehensively summarize the processes of infection and the treatment methods, review the known findings of lncRNA classification and functional mechanisms, elucidate the roles of lncRNAs in -related gastrointestinal cancer, and discuss the clinical perspectives of lncRNAs.

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