Helicobacter Pylori-Associated Immune Thrombocytopenia: Diagnostic and Therapeutic Approach

Overview

Journal Ann Afr Med

Specialty General Medicine

Date 2024 Jul 22

PMID 39034543

Authors

Siddharth Gosavi

Gokul Krishnan

Vinay Kumar

Chinmayee Anand Nityandila

Amogh Ananda Rao

Shiana Singh

Barkur Anantha Krishna Shastry

Affiliations

Soon will be listed here.

Abstract

The relationship between immune thrombocytopenia (ITP) and Helicobacterpylori infection has largely been an unexplored entity. This review article aims at focusing on the role of H. pylori in secondary ITP. We also elucidated the importance of diagnostic workup and treatment of H. pylori in this article. The mechanisms of H. pylori-associated ITP have been covered in this article. The factors determining platelet response to H. pylori eradication therapy have been mentioned. It is extremely crucial to be aware that H. pylori is a major causative pathogen for new-onset ITP as well as chronic ITP. Upper gastrointestinal endoscopic biopsy is the best invasive method for the diagnosis of the same. Further studies need to be conducted across larger, more diverse groups to validate our observation that eradication of H. pylori could aid platelet recovery in ITP.

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