Association Between Cannabis Use and Nicotine Use Persistence Among Adolescents

Overview

Journal Addict Behav

Specialties Psychiatry
Social Sciences

Date 2024 Jul 20

PMID 39032200

Authors

Dae-Hee Han

Alyssa F Harlow

Dayoung Bae

Junhan Cho

Sandrah P Eckel

Rob McConnell

Jessica L Barrington-Trimis

Janet E Audrain-McGovern

Adam M Leventhal

Affiliations

Soon will be listed here.

Abstract

Introduction: Prospective associations of adolescent cannabis use with nicotine use persistence are not well characterized but are important for informing prevention and policy. This study examined the association of 4 types of cannabis product use with subsequent persistent nicotine product use among adolescents.

Methods: We used prospective data from an adolescent cohort (14-17 years) from Southern California surveyed at baseline and at approximately 6-month follow-up (2022-2023). We incorporated three mutually non-exclusive analytic samples comprised of individuals with baseline past 6-month use of: (1) any nicotine product (N=308 [mean[SD] age = 16.3[0.6] years]), (2) e-cigarettes (n = 276), and (3) any combustible tobacco product (n = 137). Baseline past 6-month cannabis smoking, vaping, edible use, cannabidiol [CBD] or hemp product use, and any cannabis product use (yes/no) were separately modeled as predictors of past 6-month persistent use of any nicotine products, e-cigarettes, and combustible tobacco at follow-up.

Results: Baseline use of any cannabis product was associated with increased odds of persistent use of e-cigarettes or any nicotine product (adjusted odds ratio[OR] range: 1.96-2.66). Cannabis smoking was positively associated with persistent any nicotine product use (adjusted OR=2.19, 95 % CI=1.20-4.02). Cannabis smoking, vaping, and edible use predicted persistent use of e-cigarettes (adjusted OR range: 2.22-2.79). Cannabis product use did not predict combustible tobacco use persistence. Associations of CBD/hemp product use with nicotine use persistence outcomes were all non-significant.

Conclusions: Adolescents who use cannabis may be at elevated risk for persistent nicotine use.

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