Ceramide Metabolism Compartmentalized in the Endoplasmic Reticulum and Golgi Apparatus

Overview

Journal Curr Top Membr

Specialties Biochemistry
Cell Biology

Date 2024 Jul 17

PMID 39015509

Authors

Anthony H Futerman

Affiliations

Soon will be listed here.

Citing Articles

Aging of the brain, neurotrophin signaling, and Alzheimer's disease: is IGF1-R the common culprit?.

Puglielli L Neurobiol Aging. 2007; 29(6):795-811.

PMID: 17313996 PMC: 2387053. DOI: 10.1016/j.neurobiolaging.2007.01.010.

References

Durieux I, Martel M, GOT R . Solubilization of UDPglucose-ceramide glucosyltransferase from the Golgi apparatus. Biochim Biophys Acta. 1990; 1024(2):263-6. DOI: 10.1016/0005-2736(90)90352-o. View

Rosenwald A, Machamer C, Pagano R . Effects of a sphingolipid synthesis inhibitor on membrane transport through the secretory pathway. Biochemistry. 1992; 31(14):3581-90. DOI: 10.1021/bi00129a005. View

Schwarzmann G, Sandhoff K . Metabolism and intracellular transport of glycosphingolipids. Biochemistry. 1990; 29(49):10865-71. DOI: 10.1021/bi00501a001. View

Young Jr W, Lutz M, Blackburn W . Endogenous glycosphingolipids move to the cell surface at a rate consistent with bulk flow estimates. J Biol Chem. 1992; 267(17):12011-5. View

Nelson W . Regulation of cell surface polarity from bacteria to mammals. Science. 1992; 258(5084):948-55. DOI: 10.1126/science.1439806. View

Durieux I, Martel M, GOT R . Effect of phospholipids on UDP-glucose: ceramide glucosyltransferase from Golgi membranes. Int J Biochem. 1990; 22(7):709-15. DOI: 10.1016/0020-711x(90)90005-n. View

Sasaki T . Glycolipid transfer protein and intracellular traffic of glucosylceramide. Experientia. 1990; 46(6):611-6. DOI: 10.1007/BF01939700. View

Futerman A, Stieger B, Hubbard A, Pagano R . Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus. J Biol Chem. 1990; 265(15):8650-7. View

JECKEL D, Karrenbauer A, Birk R, Schmidt R, Wieland F . Sphingomyelin is synthesized in the cis Golgi. FEBS Lett. 1990; 261(1):155-7. DOI: 10.1016/0014-5793(90)80659-7. View

10.

Hirschberg K, Rodger J, Futerman A . The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver. Biochem J. 1993; 290 ( Pt 3):751-7. PMC: 1132344. DOI: 10.1042/bj2900751. View

11.

Coste H, Martel M, Azzar G, GOT R . UDPglucose-ceramide glucosyltransferase from porcine submaxillary glands is associated with the Golgi apparatus. Biochim Biophys Acta. 1985; 814(1):1-7. DOI: 10.1016/0005-2736(85)90412-2. View

12.

Collins R, Warren G . Sphingolipid transport in mitotic HeLa cells. J Biol Chem. 1992; 267(34):24906-11. View

13.

Lipsky N, Pagano R . Sphingolipid metabolism in cultured fibroblasts: microscopic and biochemical studies employing a fluorescent ceramide analogue. Proc Natl Acad Sci U S A. 1983; 80(9):2608-12. PMC: 393876. DOI: 10.1073/pnas.80.9.2608. View

14.

Hoekstra D, Kok J . Trafficking of glycosphingolipids in eukaryotic cells; sorting and recycling of lipids. Biochim Biophys Acta. 1992; 1113(3-4):277-94. DOI: 10.1016/0304-4157(92)90002-r. View

15.

Bankaitis V, AITKEN J, Cleves A, Dowhan W . An essential role for a phospholipid transfer protein in yeast Golgi function. Nature. 1990; 347(6293):561-2. DOI: 10.1038/347561a0. View

16.

Merrill Jr A, Wang E . Biosynthesis of long-chain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s). J Biol Chem. 1986; 261(8):3764-9. View

17.

Trinchera M, Fabbri M, Ghidoni R . Topography of glycosyltransferases involved in the initial glycosylations of gangliosides. J Biol Chem. 1991; 266(31):20907-12. View

18.

Futerman A, Pagano R . Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver. Biochem J. 1991; 280 ( Pt 2):295-302. PMC: 1130545. DOI: 10.1042/bj2800295. View

19.

Futerman A, Pagano R . Use of N-([1-14C]hexanoyl)-D-erythro-sphingolipids to assay sphingolipid metabolism. Methods Enzymol. 1992; 209:437-46. DOI: 10.1016/0076-6879(92)09054-7. View

20.

Pagano R, Sleight R . Defining lipid transport pathways in animal cells. Science. 1985; 229(4718):1051-7. DOI: 10.1126/science.4035344. View