Evaluation of Various Methods of Liver Measurement in Comparison to Volumetric Segmentation Based on Computed Tomography

Overview

Journal J Clin Med

Specialty General Medicine

Date 2024 Jul 13

PMID 38999200

Authors

Maciej Cebula

Angelika Biernacka

Oskar Bozek

Bartosz Kokoszka

Sylwia Kazibut

Anna Kujszczyk

Monika Kulig-Kulesza

Sandra Modlinska

Jakub Kufel

Michal Azierski

Filip Szydlo

Mateusz Winder

Joanna Pilch-Kowalczyk

Katarzyna Gruszczynska

Affiliations

Soon will be listed here.

Abstract

: A reliable assessment of liver volume, necessary before transplantation, remains a challenge. Our work aimed to assess the differences in the evaluation and measurements of the liver between independent observers and compare different formulas calculating its volume in relation to volumetric segmentation. : Eight researchers measured standard liver dimensions based on 105 abdominal computed tomography (CT) scans. Based on the results obtained, the volume of the liver was calculated using twelve different methods. An independent observer performed a volumetric segmentation of the livers based on the same CT examinations. : Significant differences were found between the formulas and in relation to volumetric segmentation, with the closest results obtained for the Heinemann et al. method. The measurements of individual observers differed significantly from one another. The observers also rated different numbers of livers as enlarged. : Due to significant differences, despite its time-consuming nature, the use of volumetric liver segmentation in the daily assessment of liver volume seems to be the most accurate method.

References

Olthof P, Van Dam R, Jovine E, Robles Campos R, De Santibanes E, Oldhafer K . Accuracy of estimated total liver volume formulas before liver resection. Surgery. 2019; 166(3):247-253. DOI: 10.1016/j.surg.2019.05.003. View

Lim M, Tan C, Cai J, Zheng J, Kow A . CT volumetry of the liver: where does it stand in clinical practice?. Clin Radiol. 2014; 69(9):887-95. DOI: 10.1016/j.crad.2013.12.021. View

Kavur A, Gezer N, Baris M, Sahin Y, Ozkan S, Baydar B . Comparison of semi-automatic and deep learning-based automatic methods for liver segmentation in living liver transplant donors. Diagn Interv Radiol. 2020; 26(1):11-21. PMC: 7075579. DOI: 10.5152/dir.2019.19025. View

Mortele K, Cantisani V, Troisi R, de Hemptinne B, Silverman S . Preoperative liver donor evaluation: Imaging and pitfalls. Liver Transpl. 2003; 9(9):S6-14. DOI: 10.1053/jlts.2003.50199. View

Urata K, Kawasaki S, Matsunami H, Hashikura Y, Ikegami T, Ishizone S . Calculation of child and adult standard liver volume for liver transplantation. Hepatology. 1995; 21(5):1317-21. View

Fu-Gui L, Lu-Nan Y, Bo L, Yong Z, Tian-Fu W, Ming-Qing X . Estimation of standard liver volume in Chinese adult living donors. Transplant Proc. 2009; 41(10):4052-6. DOI: 10.1016/j.transproceed.2009.08.079. View

Perandini S, Faccioli N, Inama M, Mucelli R . Freehand liver volumetry by using an electromagnetic pen tablet: accuracy, precision, and rapidity. J Digit Imaging. 2010; 24(2):360-5. PMC: 3056975. DOI: 10.1007/s10278-010-9291-8. View

Seppelt D, Kromrey M, Ittermann T, Kolb C, Haubold A, Kampfrath N . Reliability and accuracy of straightforward measurements for liver volume determination in ultrasound and computed tomography compared to real volumetry. Sci Rep. 2022; 12(1):12465. PMC: 9304384. DOI: 10.1038/s41598-022-16736-9. View

Pomposelli J, Tongyoo A, Wald C, Pomfret E . Variability of standard liver volume estimation versus software-assisted total liver volume measurement. Liver Transpl. 2012; 18(9):1083-92. DOI: 10.1002/lt.23461. View

10.

Hashimoto T, Sugawara Y, Tamura S, Hasegawa K, Kishi Y, Kokudo N . Estimation of standard liver volume in Japanese living liver donors. J Gastroenterol Hepatol. 2006; 21(11):1710-3. DOI: 10.1111/j.1440-1746.2006.04433.x. View

11.

Heinemann A, Wischhusen F, Puschel K, Rogiers X . Standard liver volume in the Caucasian population. Liver Transpl Surg. 1999; 5(5):366-8. DOI: 10.1002/lt.500050516. View

12.

Masperi A, Cubadda V, Bombelli L, Labruna R, Bagnardi V, Fodor C . Intra- inter-observer repeatability in liver computed tomography volumetry in patients undergoing radioembolization simulation. Abdom Radiol (NY). 2021; 46(7):3448-3455. DOI: 10.1007/s00261-021-02980-6. View

13.

Vauthey J, Abdalla E, Doherty D, Gertsch P, Fenstermacher M, Loyer E . Body surface area and body weight predict total liver volume in Western adults. Liver Transpl. 2002; 8(3):233-40. DOI: 10.1053/jlts.2002.31654. View

14.

Radtke A, Sotiropoulos G, Nadalin S, Molmenti E, Schroeder T, Lang H . Preoperative volume prediction in adult living donor liver transplantation: how much can we rely on it?. Am J Transplant. 2007; 7(3):672-9. DOI: 10.1111/j.1600-6143.2006.01656.x. View

15.

Hori M, Suzuki K, Epstein M, Baron R . Computed tomography liver volumetry using 3-dimensional image data in living donor liver transplantation: effects of the slice thickness on the volume calculation. Liver Transpl. 2011; 17(12):1427-36. PMC: 3226887. DOI: 10.1002/lt.22419. View

16.

Chan S, Liu C, Lo C, Lam B, Lee E, Wong Y . Estimating liver weight of adults by body weight and gender. World J Gastroenterol. 2006; 12(14):2217-22. PMC: 4087649. DOI: 10.3748/wjg.v12.i4.2217. View

17.

Joshi R, Singh A, Jajoo N, Pai M, Kalantri S . Accuracy and reliability of palpation and percussion for detecting hepatomegaly: a rural hospital-based study. Indian J Gastroenterol. 2004; 23(5):171-4. View

18.

Hermoye L, Laamari-Azjal I, Cao Z, Annet L, Lerut J, Dawant B . Liver segmentation in living liver transplant donors: comparison of semiautomatic and manual methods. Radiology. 2004; 234(1):171-8. DOI: 10.1148/radiol.2341031801. View

19.

Yuan D, Lu T, Wei Y, Li B, Yan L, Zeng Y . Estimation of standard liver volume for liver transplantation in the Chinese population. Transplant Proc. 2008; 40(10):3536-40. DOI: 10.1016/j.transproceed.2008.07.135. View

20.

Poovathumkadavil A, Leung K, Al Ghamdi H, Othman I, Meshikhes A . Standard formula for liver volume in Middle Eastern Arabic adults. Transplant Proc. 2010; 42(9):3600-5. DOI: 10.1016/j.transproceed.2010.07.098. View