Molecular Functions of HAX1 During Disease Progress

Overview

Journal Virus Genes

Specialties Microbiology
Molecular Biology

Date 2024 Jul 11

PMID 38992331

Authors

Dajun Zhang

Jinke Yang

Qi Huang

Dengshuai Zhao

Tianyu Wang

Dixi Yu

Limei Qin

Keshan Zhang

Affiliations

Soon will be listed here.

Abstract

HCLS1-associated protein X-1 (HAX1) is a newly discovered multifunctional cell regulatory protein that is widely expressed in cells and has a close relationship with multiple cellular proteins. HAX1 plays important roles in various processes, including the regulation of apoptosis, maintenance of mitochondrial membrane potential stability and calcium homeostasis, occurrence and development of diseases, post-transcriptional regulation of gene expression, and host immune response after viral infection. In this article, we have reviewed the research progress on the biological functions of HAX1, thereby laying a theoretical foundation for further exploration of its underlying mechanisms and targeted application.

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