Enhanced Anti-bacterial Adhesion Effect of FDMA/SR833s Based Dental Resin Composites by Using 1H,1H-heptafluorobutyl Methacrylate As Partial Diluent

Overview

Journal Biomater Investig Dent

Date 2024 Jul 9

PMID 38979097

Authors

Shengcan Zhang

Fang Liu

Jingwei He

Affiliations

Soon will be listed here.

Abstract

With the purpose of further reducing surface free energy to achieve better anti-bacterial adhesion effect of fluorinated dimethacrylate (FDMA)/tricyclo (5.2.1.0) decanedimethanol diacrylate (SR833s) based dental resin composites (DS), 1H,1H-heptafluorobutyl methacrylate (FBMA) was used to partially replace SR933s as reactive diluent. According to the degree of substitution, the obtained resin composites were marked as DSF-1 (20 wt.% of SR833s was replaced by FBMA), DSF-2 (40 wt.% of SR833s was replaced by FBMA), and DSF-3 (60 wt.% of SR833s was replaced by FBMA). Bisphenol A glycidyl dimethacrylate (Bis-GMA)/triethylene glycol dimethacrylate (TEGDMA) based resin composite (BT) was used as control. The influence of FBMA concentration on double bond conversion (DC), contact angle, surface free energy, anti-bacterial adhesion effect against (), volumetric shrinkage (VS) and shrinkage stress (SS), flexural strength (FS) and modulus (FM), water sorption (WS) and solubility (SL) were investigated. The results showed that FBMA addition could reduce surface free energy from 44.6 mN/m for DS to 32.9 mN/m for DSF-3, and lead to better anti-bacterial adhesion effect (the amounts of adherent bacteria decreased from 2.03 × 10 CFU/mm for DS to 6.44 × 10 CFU/mm for DSF-3). The FBMA had no negative effects on DC, VS, SS, WS, and SL. Too high a concentration of FBMA reduced FS and FM before water immersion, but the values were still higher than those of BT.

Citing Articles

A review of new generation of dental restorative resin composites with antibacterial, remineralizing and self-healing capabilities.

Zhang J, Yang Y, Chen Y, Chen X, Li A, Wang J Discov Nano. 2024; 19(1):189.

PMID: 39570468 PMC: 11582236. DOI: 10.1186/s11671-024-04151-0.

References

Dewaele M, Truffier-Boutry D, Devaux J, Leloup G . Volume contraction in photocured dental resins: the shrinkage-conversion relationship revisited. Dent Mater. 2005; 22(4):359-65. DOI: 10.1016/j.dental.2005.03.014. View

Liu X, Wang Z, Zhao C, Bu W, Zhang Y, Na H . Synthesis, characterization and evaluation of a fluorinated resin monomer with low water sorption. J Mech Behav Biomed Mater. 2017; 77:446-454. DOI: 10.1016/j.jmbbm.2017.09.026. View

Soares C, Faria-E-Silva A, Rodrigues M, Vilela A, Pfeifer C, Tantbirojn D . Polymerization shrinkage stress of composite resins and resin cements - What do we need to know?. Braz Oral Res. 2017; 31(suppl 1):e62. DOI: 10.1590/1807-3107BOR-2017.vol31.0062. View

Kovalchuk N, Trybala A, Starov V, Matar O, Ivanova N . Fluoro- vs hydrocarbon surfactants: why do they differ in wetting performance?. Adv Colloid Interface Sci. 2014; 210:65-71. DOI: 10.1016/j.cis.2014.04.003. View

Aljabo A, Xia W, Liaqat S, Khan M, Knowles J, Ashley P . Conversion, shrinkage, water sorption, flexural strength and modulus of re-mineralizing dental composites. Dent Mater. 2015; 31(11):1279-89. DOI: 10.1016/j.dental.2015.08.149. View

Auschill T, Arweiler N, Brecx M, Reich E, Sculean A, Netuschil L . The effect of dental restorative materials on dental biofilm. Eur J Oral Sci. 2002; 110(1):48-53. DOI: 10.1046/j.0909-8836.2001.101160.x. View

He J, Liao L, Liu F, Luo Y, Jia D . Synthesis and characterization of a new dimethacrylate monomer based on 5,50-bis(4-hydroxylphenyl)-hexahydro-4,7-methanoindan for root canal sealer application. J Mater Sci Mater Med. 2009; 21(4):1135-42. DOI: 10.1007/s10856-009-3979-7. View

He J, Garoushi S, Vallittu P, Lassila L . Effect of low-shrinkage monomers on the physicochemical properties of experimental composite resin. Acta Biomater Odontol Scand. 2018; 4(1):30-37. PMC: 5844030. DOI: 10.1080/23337931.2018.1444488. View

Beyth N, Domb A, Weiss E . An in vitro quantitative antibacterial analysis of amalgam and composite resins. J Dent. 2006; 35(3):201-6. DOI: 10.1016/j.jdent.2006.07.009. View

10.

Kilian M, Chapple I, Hannig M, Marsh P, Meuric V, Pedersen A . The oral microbiome - an update for oral healthcare professionals. Br Dent J. 2016; 221(10):657-666. DOI: 10.1038/sj.bdj.2016.865. View

11.

Cidreira Boaro L, Goncalves F, Guimaraes T, Ferracane J, Versluis A, Braga R . Polymerization stress, shrinkage and elastic modulus of current low-shrinkage restorative composites. Dent Mater. 2010; 26(12):1144-50. DOI: 10.1016/j.dental.2010.08.003. View

12.

Schneider L, Cavalcante L, Silikas N . Shrinkage Stresses Generated during Resin-Composite Applications: A Review. J Dent Biomech. 2010; 2010. PMC: 2951111. DOI: 10.4061/2010/131630. View

13.

Arima T, Hamada T, McCabe J . The effects of cross-linking agents on some properties of HEMA-based resins. J Dent Res. 1995; 74(9):1597-601. DOI: 10.1177/00220345950740091501. View

14.

Gajewski V, Pfeifer C, Froes-Salgado N, Boaro L, Braga R . Monomers used in resin composites: degree of conversion, mechanical properties and water sorption/solubility. Braz Dent J. 2013; 23(5):508-14. DOI: 10.1590/s0103-64402012000500007. View

15.

He J, Lassila L, Garoushi S, Vallittu P . Tailoring the monomers to overcome the shortcomings of current dental resin composites - review. Biomater Investig Dent. 2023; 10(1):2191621. PMC: 10120559. DOI: 10.1080/26415275.2023.2191621. View

16.

Ferracane J . Hygroscopic and hydrolytic effects in dental polymer networks. Dent Mater. 2005; 22(3):211-22. DOI: 10.1016/j.dental.2005.05.005. View

17.

Quirynen M, Marechal M, Busscher H, Weerkamp A, Darius P, van Steenberghe D . The influence of surface free energy and surface roughness on early plaque formation. An in vivo study in man. J Clin Periodontol. 1990; 17(3):138-44. DOI: 10.1111/j.1600-051x.1990.tb01077.x. View

18.

Lu H, Stansbury J, Nie J, Berchtold K, Bowman C . Development of highly reactive mono-(meth)acrylates as reactive diluents for dimethacrylate-based dental resin systems. Biomaterials. 2004; 26(12):1329-36. DOI: 10.1016/j.biomaterials.2004.04.041. View

19.

Goldman M . Polymerization shrinkage of resin-based restorative materials. Aust Dent J. 1983; 28(3):156-61. DOI: 10.1111/j.1834-7819.1983.tb05272.x. View

20.

He J, Stenhagen I, Dragland I, Kopperud H . Preparation of a fluorinated dental resin system and its anti-adhesive properties against S. mutans. Dent Mater. 2023; 39(4):402-409. DOI: 10.1016/j.dental.2023.03.009. View