Inequality in Female Breast Cancer Relative Survival Rates Between White and Black Women in the United States

Overview

Journal J Racial Ethn Health Disparities

Specialties Public Health
Social Sciences

Date 2024 Jul 3

PMID 38961004

Authors

Ray M Merrill

Ian S Gibbons

Affiliations

Soon will be listed here.

Abstract

Background: This study assessed the difference in 3-, 5-, and 10-year relative survival rates (RSRs) for female breast cancer between White and Black patients across the levels of year, tumor stage, age, and marital status at diagnosis. Confounding factors and effect modifiers were considered.

Methods: Analyses were based on 17 population-based tumor registries in the Surveillance, Epidemiology, and End Results (SEER) Program. Cases were diagnosed in 2000-2017 and followed through 2020.

Results: Three-, 5-, and 10-year female breast cancer RSRs significantly improved for White and Black patients during the years 2000-2020, more so for Blacks than Whites. Three-, 5-, and 10-year estimated annual percent changes in trends were 0.09%, 0.16%, and 0.29% for Whites and 0.36%, 0.49%, and 0.86% for Blacks, respectively. However, a large difference in RSRs for White and Black patients persists, 4.2% for three-year RSRs, 5.7% for five-year RSRs, and 7.5% for 10-year RSRs, after adjusting for year, tumor stage, age, and marital status at diagnosis. The difference in RSRs between White and Black patients differs by tumor stage at diagnosis. For example, higher five-year RSRs in Whites than Blacks were 2.6% for local, 9.3% for regional, 10.4% for distant, and 6.2% for unknown/unstaged tumors at diagnosis.

Conclusion: Improvement in 3-, 5-, and 10-year female breast cancer RSRs occurred for both White and Black patients, albeit more so for Blacks. Yet the poorer RSRs for Blacks remain large and significant, increasingly so with later staged disease at diagnosis and as we move from 3- to 5- to 10-year RSRs.

References

Yedjou C, Sims J, Miele L, Noubissi F, Lowe L, Fonseca D . Health and Racial Disparity in Breast Cancer. Adv Exp Med Biol. 2019; 1152:31-49. PMC: 6941147. DOI: 10.1007/978-3-030-20301-6_3. View

Giaquinto A, Miller K, Tossas K, Winn R, Jemal A, Siegel R . Cancer statistics for African American/Black People 2022. CA Cancer J Clin. 2022; 72(3):202-229. DOI: 10.3322/caac.21718. View

Baquet C, Mishra S, Commiskey P, Ellison G, DeShields M . Breast cancer epidemiology in blacks and whites: disparities in incidence, mortality, survival rates and histology. J Natl Med Assoc. 2008; 100(5):480-8. PMC: 3603001. DOI: 10.1016/s0027-9684(15)31294-3. View

Abraham H, Xia Y, Mukherjee B, Merajver S . Incidence and survival of inflammatory breast cancer between 1973 and 2015 in the SEER database. Breast Cancer Res Treat. 2020; 185(1):229-238. DOI: 10.1007/s10549-020-05938-2. View

George P, Chandwani S, Gabel M, Ambrosone C, Rhoads G, Bandera E . Diagnosis and surgical delays in African American and white women with early-stage breast cancer. J Womens Health (Larchmt). 2015; 24(3):209-17. PMC: 4442576. DOI: 10.1089/jwh.2014.4773. View

Fontein D, de Glas N, Duijm M, Bastiaannet E, Portielje J, van de Velde C . Age and the effect of physical activity on breast cancer survival: A systematic review. Cancer Treat Rev. 2013; 39(8):958-65. DOI: 10.1016/j.ctrv.2013.03.008. View

Li X, Yang J, Peng L, Sahin A, Huo L, Ward K . Triple-negative breast cancer has worse overall survival and cause-specific survival than non-triple-negative breast cancer. Breast Cancer Res Treat. 2016; 161(2):279-287. DOI: 10.1007/s10549-016-4059-6. View

Adekolujo O, Tadisina S, Koduru U, Gernand J, Smith S, Kakarala R . Impact of Marital Status on Tumor Stage at Diagnosis and on Survival in Male Breast Cancer. Am J Mens Health. 2016; 11(4):1190-1199. PMC: 5675311. DOI: 10.1177/1557988316669044. View

Hankey B, Ries L, Edwards B . The surveillance, epidemiology, and end results program: a national resource. Cancer Epidemiol Biomarkers Prev. 1999; 8(12):1117-21. View

10.

ZIPPIN C, Lum D, Hankey B . Completeness of hospital cancer case reporting from the SEER Program of the National Cancer Institute. Cancer. 1995; 76(11):2343-50. DOI: 10.1002/1097-0142(19951201)76:11<2343::aid-cncr2820761124>3.0.co;2-#. View

11.

Mariotto A, Noone A, Howlader N, Cho H, Keel G, Garshell J . Cancer survival: an overview of measures, uses, and interpretation. J Natl Cancer Inst Monogr. 2014; 2014(49):145-86. PMC: 4829054. DOI: 10.1093/jncimonographs/lgu024. View

12.

Bleyer A, Welch H . Effect of three decades of screening mammography on breast-cancer incidence. N Engl J Med. 2012; 367(21):1998-2005. DOI: 10.1056/NEJMoa1206809. View

13.

Mitchell E . Cancer in African Americans: Screening can make a Difference. J Natl Med Assoc. 2021; 113(4):365. DOI: 10.1016/j.jnma.2021.07.001. View

14.

Aleshire M, Adegboyega A, Escontrias O, Edward J, Hatcher J . Access to Care as a Barrier to Mammography for Black Women. Policy Polit Nurs Pract. 2020; 22(1):28-40. PMC: 8175007. DOI: 10.1177/1527154420965537. View

15.

Oppong B, Obeng-Gyasi S, Relation T, Adams-Campbell L . Call to action: breast cancer screening recommendations for Black women. Breast Cancer Res Treat. 2021; 187(1):295-297. DOI: 10.1007/s10549-021-06207-6. View

16.

Coleman C . Early Detection and Screening for Breast Cancer. Semin Oncol Nurs. 2017; 33(2):141-155. DOI: 10.1016/j.soncn.2017.02.009. View

17.

Reisch L, Barton M, Fletcher S, Kreuter W, Elmore J . Breast cancer screening use by African Americans and Whites in an HMO. J Gen Intern Med. 2000; 15(4):229-34. PMC: 1495437. DOI: 10.1111/j.1525-1497.2000.01339.x. View

18.

Raley R, Sweeney M, Wondra D . The Growing Racial and Ethnic Divide in U.S. Marriage Patterns. Future Child. 2016; 25(2):89-109. PMC: 4850739. DOI: 10.1353/foc.2015.0014. View

19.

Giaquinto A, Sung H, Miller K, Kramer J, Newman L, Minihan A . Breast Cancer Statistics, 2022. CA Cancer J Clin. 2022; 72(6):524-541. DOI: 10.3322/caac.21754. View

20.

Nardin S, Mora E, Varughese F, DAvanzo F, Vachanaram A, Rossi V . Breast Cancer Survivorship, Quality of Life, and Late Toxicities. Front Oncol. 2020; 10:864. PMC: 7308500. DOI: 10.3389/fonc.2020.00864. View