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Factors Affecting Asthma Control in Pregnancy: A Cross-sectional Study

Overview
Journal Pak J Med Sci
Specialty General Medicine
Date 2024 Jul 2
PMID 38952503
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Abstract

Background And Objective: Asthma control in pregnant women remains of utmost importance; suboptimal control can have adverse repercussions on both fetal and maternal health. The objective was to identify the factors that affect asthma control in pregnant Pakistani women presenting to a tertiary care hospital.

Methods: This descriptive, cross-sectional research was conducted at KRL General Hospital between 1 November 2022 to 30 April 2023. Non-probability technique was used to sample one hundred and forty-five pregnant women with confirmed bronchial asthma irrespective of their trimester presented. Data regarding demographics and factors affecting asthma control was collected.

Results: The mean age was 30.39 ± 4.33 years, with two-thirds (65%) being multiparous. Approximately 48% of participants were non-compliant with treatment, and less than 40% achieved adequate asthma control. A chi-squared test applied showed that multiparity (p = 0.003), treatment compliance (p < 0.001), BMI (p < 0.001), and proper inhaler technique (p < 0.001) were statistically significant factors affecting asthma control in pregnant women while, the level of education and household income did not exhibit a significant association. Multiple regression analysis qualified higher BMI, multiparity, treatment compliance, and inhaler technique as significant predictors of asthma control amongst pregnant women.

Conclusion: Ensuring asthma control during pregnancy is important. This study identified BMI, multiparity, inhaler technique, and treatment compliance as factors that affect asthma control in pregnant women. Addressing these factors through regular antenatal check-ups can significantly mitigate risks and promote the optimal health of both maternal and fetal lives.

References
1.
Yland J, Bateman B, Huybrechts K, Brill G, Schatz M, Wurst K . Perinatal Outcomes Associated with Maternal Asthma and Its Severity and Control During Pregnancy. J Allergy Clin Immunol Pract. 2020; 8(6):1928-1937.e3. DOI: 10.1016/j.jaip.2020.01.016. View

2.
Flores K, Bandoli G, Chambers C, Schatz M, Palmsten K . Asthma prevalence among women aged 18 to 44 in the United States: National health and nutrition examination survey 2001-2016. J Asthma. 2019; 57(7):693-702. PMC: 7135309. DOI: 10.1080/02770903.2019.1602874. View

3.
Chogtu B, Holla S, Magazine R, Kamath A . Evaluation of relationship of inhaler technique with asthma control and quality of life. Indian J Pharmacol. 2017; 49(1):110-115. PMC: 5351222. DOI: 10.4103/0253-7613.201012. View

4.
Williams L, Peterson E, Wells K, Ahmedani B, Kumar R, Burchard E . Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence. J Allergy Clin Immunol. 2011; 128(6):1185-1191.e2. PMC: 3229671. DOI: 10.1016/j.jaci.2011.09.011. View

5.
Kemppainen M, Lahesmaa-Korpinen A, Kauppi P, Virtanen M, Virtanen S, Karikoski R . Maternal asthma is associated with increased risk of perinatal mortality. PLoS One. 2018; 13(5):e0197593. PMC: 5959067. DOI: 10.1371/journal.pone.0197593. View