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Sarcopenic Obesity in Patients Awaiting Liver Transplant: Unique Challenges for Nutritional Recommendations

Overview
Specialty General Surgery
Date 2024 Jul 1
PMID 38947969
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Abstract

Sarcopenic obesity increases the risk of mortality in patients with liver disease awaiting liver transplantation and in the post-transplant period. Nutrition recommendations for individuals with sarcopenia differ from recommendations for patients with obesity or sarcopenic obesity. While these nutrition guidelines have been established in non-cirrhotic patients, established guidelines for liver transplant candidates with sarcopenic obesity are lacking. In this paper, we review existing literature on sarcopenic obesity in patients with chronic liver disease and address opportunities to improve nutritional counseling in patients awaiting liver transplantation.

References
1.
Hegyi P, Soos A, Hegyi P, Szakacs Z, Hanak L, Vancsa S . Pre-transplant Sarcopenic Obesity Worsens the Survival After Liver Transplantation: A Meta-Analysis and a Systematic Review. Front Med (Lausanne). 2021; 7:599434. PMC: 7772841. DOI: 10.3389/fmed.2020.599434. View

2.
Eslamparast T, Montano-Loza A, Raman M, Tandon P . Sarcopenic obesity in cirrhosis-The confluence of 2 prognostic titans. Liver Int. 2018; 38(10):1706-1717. DOI: 10.1111/liv.13876. View

3.
Kamo N, Kaido T, Hamaguchi Y, Okumura S, Kobayashi A, Shirai H . Impact of sarcopenic obesity on outcomes in patients undergoing living donor liver transplantation. Clin Nutr. 2018; 38(5):2202-2209. DOI: 10.1016/j.clnu.2018.09.019. View

4.
Huh J, Dincer F, Mesfum E, Mantzoros C . Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans. Int J Obes (Lond). 2014; 38(12):1538-44. DOI: 10.1038/ijo.2014.42. View

5.
Yun J, Kwon R, Kim T . Prevalence and clinical characteristics of low skeletal muscle index among adults visiting a health promotion center: Cross-sectional study. Medicine (Baltimore). 2023; 102(29):e34404. PMC: 10662807. DOI: 10.1097/MD.0000000000034404. View