Rapid Mode Switching Facilitates the Growth of : A Model Analysis

Overview

Journal iScience

Publisher Cell Press

Date 2024 Jul 1

PMID 38947530

Authors

Meng Gao

Jamal Andrews

Gabrielle Armin

Subhendu Chakraborty

Jonathan P Zehr

Keisuke Inomura

Affiliations

Soon will be listed here.

Abstract

is one of the dominant dinitrogen (N) fixers in the ocean, influencing global carbon and nitrogen cycles through biochemical reactions. Although its photosynthetic activity fluctuates rapidly, the physiological or ecological advantage of this fluctuation is unclear. We develop a metabolic model of that can perform daytime N fixation. We examined (1) the effect of the duration of switches between photosynthetic and non-photosynthetic cellular states and (2) the effect of the presence and absence of N fixation in photosynthetic states. Results show that a rapid switch between photosynthetic and non-photosynthetic states increases growth rates by improving metabolic efficiencies due to an improved balance of C and N metabolism. This provides a strategy for previous paradoxical observations that all cells can contain nitrogenase. This study reveals the importance of fluctuating photosynthetic activity and provides a mechanism for daytime N fixation that allows to fix N aerobically in the global ocean.

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