A Simplified GBR Treatment and Evaluation of Posterior Seibert Class I Ridge Defects Via Bio-collagen and Platelet-Rich Fibrin: A Retrospective Study

Overview

Journal Tissue Eng Regen Med

Date 2024 Jun 28

PMID 38943036

Authors

Zhi Wang

Yafeng Zheng

Jiaqi Xu

Qi Jia

Heng Bo Jiang

Eui-Seok Lee

Affiliations

Soon will be listed here.

Abstract

Background: Classical guided bone regeneration (GBR) treatments can achieve favorable clinical results for ridge defects. However, extensive bone augmentation in the non-esthetic area in the posterior region for minor ridge defects is unnecessary. Therefore, this study used a collagen and Platelet-rich fibrin (PRF) mixture for bone augmentation on minor posterior ridge defects and evaluated the effects.

Methods: 22 Seibert Class I ridge defects were treated with BC and covered with a PRF membrane (simplified guided bone regeneration, simplified GBR) and other 22 were treated with Bio-Oss and covered with Bio-Gide (classical GBR). Cone-beam computed tomography imaging was conducted 6 months post-surgery to compare the ridge's horizontal width (HW) and buccal ridge's horizontal width to assess the osteogenic effect. In addition, the buccal ridge contour morphology was studied and classified.

Results: The buccal ridge contour of simplified GBR was Type A in 14 cases, Type B in 7 cases, and Type C in 1 case and it of classical GBR was Type A in 11 cases, Type B in 8 cases, and Type C in 3 cases. The mean HW significantly increased by 1.50 mm of simplified GBR treatment, while it increased by 1.83 mm in classical GBR treatment.

Conclusion: The combined use of BC and PRF had a significant effect on bone augmentation and this treatment exhibited promising clinical results for correcting posterior Seibert Class I ridge defects. The morphological classification of the reconstructive effect in this study can be utilized in future clinical work.

Citing Articles

GBR assisted Onlay bone grafting for the posterior maxillary horizontal ridge augmentation: a case report and literature review.

Li M, Liu X, Zhou J, You J, Chen S, Feng J Front Bioeng Biotechnol. 2025; 12:1535207.

PMID: 39867470 PMC: 11757243. DOI: 10.3389/fbioe.2024.1535207.

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