Advances in Liquid Biopsy in Neuroblastoma

Overview

Journal Fundam Res

Date 2024 Jun 27

PMID 38933377

Authors

Zhenjian Zhuo

Lei Lin

Lei Miao

Meng Li

Jing He

Affiliations

Soon will be listed here.

Abstract

Even with intensive treatment of high-risk neuroblastoma (NB) patients, half of high-risk NB patients still relapse. New therapies targeting the biological characteristics of NB have important clinical value for the personalized treatment of NB. However, the current biological markers for NB are mainly analyzed by tissue biopsy. In recent years, circulating biomarkers of NB based on liquid biopsy have attracted more and more attention. This review summarizes the analytes and methods for liquid biopsy of NB. We focus on the application of liquid biopsy in the diagnosis, prognosis assessment, and monitoring of NB. Finally, we discuss the prospects and challenges of liquid biopsy in NB.

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