Nanoarchitectonics-Based Materials As a Promising Strategy in the Treatment of Endodontic Infections

Overview

Journal Pharmaceutics

Publisher MDPI

Date 2024 Jun 27

PMID 38931881

Authors

Suli Xiao

Guanwen Sun

Shan Huang

Chen Lin

Yijun Li

Affiliations

Soon will be listed here.

Abstract

Endodontic infections arise from the interactive activities of microbial communities colonizing in the intricate root canal system. The present study aims to update the latest knowledge of nanomaterials, their antimicrobial mechanisms, and their applications in endodontics. A detailed literature review of the current knowledge of nanomaterials used in endodontic applications was performed using the PubMed database. Antimicrobial nanomaterials with a small size, large specific surface area, and high chemical activity are introduced to act as irrigants, photosensitizer delivery systems, and medicaments, or to modify sealers. The application of nanomaterials in the endodontic field could enhance antimicrobial efficiency, increase dentin tubule penetration, and improve treatment outcomes. This study supports the potential of nanomaterials as a promising strategy in treating endodontic infections.

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