Cancer Incidence Relation to Heavy Metals in Soils of Kyzylorda Region of Kazakhstan

Overview

Journal Asian Pac J Cancer Prev

Specialty Oncology

Date 2024 Jun 25

PMID 38918660

Authors

Farida Rakhimbekova

Dilyara R Kaidarova

Madina Orazgalieva

Zhassulan Ryspambetov

Anton Buzdin

Bakytzhan Anapiyayev

Affiliations

Soon will be listed here.

Abstract

Objective: The purpose of this study was to investigate the relationship of soil pollution factors such as heavy metal ions with the incidence of cancer in the Kyzylorda region of Kazakhstan.

Methods: Concentrations of heavy metal ions in the soils of different sites of Kyzylorda region, Kazakhstan, were sampled and correlated with incidence of cancer in 2021.

Results: Chromium content in the soil exceeded maximum permissible concentration (MPC) in the samples for all sites except Kazaly and Shieli, and the highest excess of 2.8 MPC was found in Terenozek. Content of copper, lead, and cobalt ions was also increased and varied in the range 1.9-15.4, 1.2-4, and 1.2-2.44 MPC, respectively. In addition, lung cancer incidence was statistically significantly correlated with soil concentration to MPC ratio of copper, cobalt, and lead; colorectal cancer was correlated with soil concentration of chromium. Cases of invasive cancer and mutations were recorded Terenozek and Kyzylorda areas.

Conclusion: The higher the soil concentration correlate with higher cancer incidence in Kyzylorda region, Kazakhstan.

Citing Articles

In-depth analysis and trends of cancer mortality in Kazakhstan: a joinpoint analysis of nationwide healthcare data 2014-2022.

Akhmedullin R, Aimyshev T, Zhakhina G, Yerdessov S, Beyembetova A, Ablayeva A BMC Cancer. 2024; 24(1):1340.

PMID: 39482619 PMC: 11526534. DOI: 10.1186/s12885-024-13128-2.

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