In Search of a Function for the Invariant Chain Associated with Ia Antigens

Overview

Journal Surv Immunol Res

Publisher Karger

Specialty Allergy & Immunology

Date 1985 Jan 1

PMID 3890055

Citations 21

Authors

E O Long

Affiliations

Soon will be listed here.

Citing Articles

Mutant human cells defective in induction of major histocompatibility complex class II genes by interferon gamma.

Mao C, Davies D, Kerr I, Stark G Proc Natl Acad Sci U S A. 1993; 90(7):2880-4.

PMID: 8464903 PMC: 46200. DOI: 10.1073/pnas.90.7.2880.

Chloroquine affects biosynthesis of Ia molecules by inhibiting dissociation of invariant (gamma) chains from alpha-beta dimers in B cells.

Nowell J, Quaranta V J Exp Med. 1985; 162(4):1371-6.

PMID: 3930653 PMC: 2187864. DOI: 10.1084/jem.162.4.1371.

The membrane-spanning segment of invariant chain (I gamma) contains a potentially cleavable signal sequence.

Lipp J, Dobberstein B Cell. 1986; 46(7):1103-12.

PMID: 3530500 PMC: 7133317. DOI: 10.1016/0092-8674(86)90710-5.

Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain.

Miller J, Germain R J Exp Med. 1986; 164(5):1478-89.

PMID: 3464691 PMC: 2188439. DOI: 10.1084/jem.164.5.1478.

Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes.

OSullivan D, Larhammar D, Wilson M, Peterson P, Quaranta V Proc Natl Acad Sci U S A. 1986; 83(12):4484-8.

PMID: 3459184 PMC: 323758. DOI: 10.1073/pnas.83.12.4484.

References

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Singer P, Lauer W, Dembic Z, MAYER W, Lipp J, Koch N . Structure of the murine Ia-associated invariant (Ii) chain as deduced from a cDNA clone. EMBO J. 1984; 3(4):873-7. PMC: 557441. DOI: 10.1002/j.1460-2075.1984.tb01899.x. View

Claesson L, Peterson P . Association of human gamma chain with class II transplantation antigens during intracellular transport. Biochemistry. 1983; 22(13):3206-13. DOI: 10.1021/bi00282a026. View

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Rahmsdorf H, Koch N, Mallick U, Herrlich P . Regulation of MHC class II invariant chain expression: induction of synthesis in human and murine plasmocytoma cells by arresting replication. EMBO J. 1983; 2(6):811-6. PMC: 555194. DOI: 10.1002/j.1460-2075.1983.tb01507.x. View

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Thinnes F, Hilschmann N, Kayser H, Gotz H . [Is the HLA-DR associated glycoprotein p31 a ubiquitous molecule?]. Hoppe Seylers Z Physiol Chem. 1983; 364(12):1805-11. DOI: 10.1515/bchm2.1983.364.2.1805. View

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Reske K, Zecher R, STENGER E . Mouse invariant chain gamma exhibits structural homology to both polymorphic subunits of the alpha, beta-core complex of I-Ak antigens. FEBS Lett. 1983; 159(1-2):153-7. DOI: 10.1016/0014-5793(83)80436-0. View

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Strubin M, MACH B, Long E . The complete sequence of the mRNA for the HLA-DR-associated invariant chain reveals a polypeptide with an unusual transmembrane polarity. EMBO J. 1984; 3(4):869-72. PMC: 557440. DOI: 10.1002/j.1460-2075.1984.tb01898.x. View

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Collins T, Korman A, Wake C, Boss J, Kappes D, Fiers W . Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts. Proc Natl Acad Sci U S A. 1984; 81(15):4917-21. PMC: 391603. DOI: 10.1073/pnas.81.15.4917. View

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Quaranta V, Majdic O, Stingl G, Liszka K, Honigsmann H, Knapp W . A human Ia cytoplasmic determinant located on multiple forms of invariant chain (gamma, gamma 2, gamma 3). J Immunol. 1984; 132(4):1900-5. View

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Machamer C, Cresswell P . Monensin prevents terminal glycosylation of the N- and O-linked oligosaccharides of the HLA-DR-associated invariant chain and inhibits its dissociation from the alpha-beta chain complex. Proc Natl Acad Sci U S A. 1984; 81(5):1287-91. PMC: 344818. DOI: 10.1073/pnas.81.5.1287. View

20.

Owen M, Kissonerghis A, Lodish H, Crumpton M . Biosynthesis and maturation of HLA-DR antigens in vivo. J Biol Chem. 1981; 256(17):8987-93. View