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» Articles » PMID: 38890660

Digital Ischemic Necrosis in a Patient with Systematic Lupus Erythematosus Patient After Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Case Report

Overview
Journal J Med Case Rep
Publisher Biomed Central
Specialty General Medicine
Date 2024 Jun 18
PMID 38890660
Authors
Jia-Hao Wen
Kai Zheng
Hua-Liang Ren
Wang-De Zhang
Chun-Min Li
Affiliations
Soon will be listed here.
Abstract

Background: Patients with coronavirus disease 2019 have a high incidence of thrombosis that decreases after recovery. When coronavirus disease 2019 is accompanied by diseases prone to thrombosis, risk of post-infection thrombotic events may increase.

Case Presentation: We report a case of digital ischemic gangrene in a 24-year-old Chinese female with systemic lupus erythematosus after recovery from coronavirus disease 2019. The pathogenesis was related to clinical characteristics of systemic lupus erythematosus, hypercoagulability caused by coronavirus disease 2019, and second-hit due to viral infection.

Conclusion: Patients with autoimmune diseases should remain alert to autoimmune system disorders induced by severe acute respiratory syndrome coronavirus 2 and other viruses. Treatment for these patients should be strictly standardized, and appropriate anticoagulation methods should be selected to prevent thrombosis.

References
1.
Quaglia M, Merlotti G, De Andrea M, Borgogna C, Cantaluppi V . Viral Infections and Systemic Lupus Erythematosus: New Players in an Old Story. Viruses. 2021; 13(2). PMC: 7916951. DOI: 10.3390/v13020277. View
2.
Ulanowska M, Olas B . Modulation of Hemostasis in COVID-19; Blood Platelets May Be Important Pieces in the COVID-19 Puzzle. Pathogens. 2021; 10(3). PMC: 8003436. DOI: 10.3390/pathogens10030370. View
3.
Galyfos G, Sianou A, Frountzas M, Vasilios K, Vouros D, Theodoropoulos C . Acute limb ischemia among patients with COVID-19 infection. J Vasc Surg. 2021; 75(1):326-342. PMC: 8358086. DOI: 10.1016/j.jvs.2021.07.222. View
4.
Durcan L, ODwyer T, Petri M . Management strategies and future directions for systemic lupus erythematosus in adults. Lancet. 2019; 393(10188):2332-2343. DOI: 10.1016/S0140-6736(19)30237-5. View
5.
Tektonidou M, Laskari K, Panagiotakos D, Moutsopoulos H . Risk factors for thrombosis and primary thrombosis prevention in patients with systemic lupus erythematosus with or without antiphospholipid antibodies. Arthritis Rheum. 2009; 61(1):29-36. DOI: 10.1002/art.24232. View