Interoception in Anxiety, Depression, and Psychosis: a Review

Overview

Journal EClinicalMedicine

Specialty General Medicine

Date 2024 Jun 14

PMID 38873633

Authors

Paul M Jenkinson

Aikaterini Fotopoulou

Agustin Ibanez

Susan Rossell

Affiliations

Soon will be listed here.

Abstract

Funding: Wellcome Trust UK.

Citing Articles

Exploring the Link Between Interoception and Symptom Severity in Premature Ventricular Contractions.

Limonova A, Minenko I, Sukmanova A, Kutsenko V, Kulikova S, Nazarova M J Clin Med. 2025; 13(24.

PMID: 39768680 PMC: 11676546. DOI: 10.3390/jcm13247756.

Heart-Brain Axis: A Narrative Review of the Interaction between Depression and Arrhythmia.

Fang S, Zhang W Biomedicines. 2024; 12(8).

PMID: 39200183 PMC: 11351688. DOI: 10.3390/biomedicines12081719.

References

Paulus M, Stein M . Interoception in anxiety and depression. Brain Struct Funct. 2010; 214(5-6):451-63. PMC: 2886901. DOI: 10.1007/s00429-010-0258-9. View

Nord C, Garfinkel S . Interoceptive pathways to understand and treat mental health conditions. Trends Cogn Sci. 2022; 26(6):499-513. DOI: 10.1016/j.tics.2022.03.004. View

Ibanez A, Northoff G . Intrinsic timescales and predictive allostatic interoception in brain health and disease. Neurosci Biobehav Rev. 2023; 157:105510. PMC: 11184903. DOI: 10.1016/j.neubiorev.2023.105510. View

Palser E, Galvez-Pol A, Palmer C, Hannah R, Fotopoulou A, Pellicano E . Reduced differentiation of emotion-associated bodily sensations in autism. Autism. 2021; 25(5):1321-1334. DOI: 10.1177/1362361320987950. View

Suksasilp C, Garfinkel S . Towards a comprehensive assessment of interoception in a multi-dimensional framework. Biol Psychol. 2022; 168:108262. DOI: 10.1016/j.biopsycho.2022.108262. View

Wise T, Robinson O, Gillan C . Identifying Transdiagnostic Mechanisms in Mental Health Using Computational Factor Modeling. Biol Psychiatry. 2023; 93(8):690-703. PMC: 10017264. DOI: 10.1016/j.biopsych.2022.09.034. View

Whitehead W, Drescher V, Heiman P, Blackwell B . Realtion of heart rate control to heartbeat perception. Biofeedback Self Regul. 1977; 2(4):317-92. View

de Jong M, Lazar S, Hug K, Mehling W, Holzel B, Sack A . Effects of Mindfulness-Based Cognitive Therapy on Body Awareness in Patients with Chronic Pain and Comorbid Depression. Front Psychol. 2016; 7:967. PMC: 4927571. DOI: 10.3389/fpsyg.2016.00967. View

Ma-Kellams C . Cross-cultural differences in somatic awareness and interoceptive accuracy: a review of the literature and directions for future research. Front Psychol. 2014; 5:1379. PMC: 4253951. DOI: 10.3389/fpsyg.2014.01379. View

10.

Paulus M . The breathing conundrum-interoceptive sensitivity and anxiety. Depress Anxiety. 2013; 30(4):315-20. PMC: 3805119. DOI: 10.1002/da.22076. View

11.

Hechler T . Altered interoception and its role for the co-occurrence of chronic primary pain and mental health problems in children. Pain. 2020; 162(3):665-671. DOI: 10.1097/j.pain.0000000000002099. View

12.

Torregrossa L, Amedy A, Roig J, Prada A, Park S . Interoceptive functioning in schizophrenia and schizotypy. Schizophr Res. 2021; 239:151-159. DOI: 10.1016/j.schres.2021.11.046. View

13.

Harrison O, Kochli L, Marino S, Luechinger R, Hennel F, Brand K . Interoception of breathing and its relationship with anxiety. Neuron. 2021; 109(24):4080-4093.e8. PMC: 8691949. DOI: 10.1016/j.neuron.2021.09.045. View

14.

Chen W, Schloesser D, Arensdorf A, Simmons J, Cui C, Valentino R . The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self. Trends Neurosci. 2020; 44(1):3-16. PMC: 7780231. DOI: 10.1016/j.tins.2020.10.007. View

15.

Farb N, Daubenmier J, Price C, Gard T, Kerr C, Dunn B . Interoception, contemplative practice, and health. Front Psychol. 2015; 6:763. PMC: 4460802. DOI: 10.3389/fpsyg.2015.00763. View

16.

Smith R, Kuplicki R, Feinstein J, Forthman K, Stewart J, Paulus M . A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders. PLoS Comput Biol. 2020; 16(12):e1008484. PMC: 7769623. DOI: 10.1371/journal.pcbi.1008484. View

17.

Seth A, Friston K . Active interoceptive inference and the emotional brain. Philos Trans R Soc Lond B Biol Sci. 2017; 371(1708). PMC: 5062097. DOI: 10.1098/rstb.2016.0007. View

18.

Legrand N, Nikolova N, Correa C, Braendholt M, Stuckert A, Kildahl N . The heart rate discrimination task: A psychophysical method to estimate the accuracy and precision of interoceptive beliefs. Biol Psychol. 2021; 168:108239. DOI: 10.1016/j.biopsycho.2021.108239. View

19.

Savitz J, Harrison N . Interoception and Inflammation in Psychiatric Disorders. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018; 3(6):514-524. PMC: 5995132. DOI: 10.1016/j.bpsc.2017.12.011. View

20.

Khalsa S, Adolphs R, Cameron O, Critchley H, Davenport P, Feinstein J . Interoception and Mental Health: A Roadmap. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018; 3(6):501-513. PMC: 6054486. DOI: 10.1016/j.bpsc.2017.12.004. View