Sensory Encoding and Memory in the Mushroom Body: Signals, Noise, and Variability

Overview

Journal Learn Mem

Specialty Neurology

Date 2024 Jun 11

PMID 38862174

Authors

Moshe Parnas

Julia E Manoim

Andrew C Lin

Affiliations

Soon will be listed here.

Abstract

To survive in changing environments, animals need to learn to associate specific sensory stimuli with positive or negative valence. How do they form stimulus-specific memories to distinguish between positively/negatively associated stimuli and other irrelevant stimuli? Solving this task is one of the functions of the mushroom body, the associative memory center in insect brains. Here we summarize recent work on sensory encoding and memory in the mushroom body, highlighting general principles such as pattern separation, sparse coding, noise and variability, coincidence detection, and spatially localized neuromodulation, and placing the mushroom body in comparative perspective with mammalian memory systems.

Citing Articles

What do the mushroom bodies do for the insect brain? Twenty-five years of progress.

Fiala A, Kaun K Learn Mem. 2024; 31(5).

PMID: 38862175 PMC: 11199942. DOI: 10.1101/lm.053827.123.

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