Light- and Electron-microscopic Demonstration of Enkephalin-like Immunoreactivity in Paraganglia of the Human Urinary Bladder

Overview

Journal Cell Tissue Res

Specialties Anatomy & Histology
Cell Biology

Date 1985 Jan 1

PMID 3886151

Citations 5

Authors

A Vaalasti

M Pelto-Huikko

H Tainio

A Hervonen

Affiliations

Soon will be listed here.

Abstract

The distribution of enkephalin-like immunoreactivity in paraganglia of the urinary bladder of adult humans was studied by use of immuno-electron microscopy. All paraganglionic cells were positively stained. Enkephalin-like immunoreactivity was located in chromaffin granules. Chromaffin cells in the paraganglia showed only few degenerative features, suggesting undisturbed function of the cells.

Citing Articles

Multiple minute nests of incidentally detected paraganglionic cells associated with urothelial carcinoma of the urinary bladder in a 73-year-old woman.

Ohtsuki Y, Ochi K, Okada Y, Lee G, Furihata M Med Mol Morphol. 2008; 41(1):62-5.

PMID: 18470683 DOI: 10.1007/s00795-007-0380-9.

Immunohistochemical characteristics of human paraganglion cells and sensory corpuscles associated with the urinary bladder. A developmental study in the male fetus, neonate and infant.

Dixon J, Jen P, Gosling J J Anat. 1998; 192 ( Pt 3):407-15.

PMID: 9688506 PMC: 1467784. DOI: 10.1046/j.1469-7580.1998.19230407.x.

Galanin-, neuropeptide Y- and enkephalin-like immunoreactivities in catecholamine-storing paraganglia of the fetal guinea pig and newborn pig.

Fried G, Meister B, Wikstrom M, Terenius L, Goldstein M Cell Tissue Res. 1989; 255(3):495-504.

PMID: 2468416 DOI: 10.1007/BF00218784.

Enkephalin- and serotonin-like immunoreactivity in the aortico-pulmonary paraganglia of the white-belly opossum Didelphis albiventris (Marsupialia).

Gobbi H, Barbosa A, Nogueira J, Polak J, Teixeira V, Almeida H Histochem J. 1992; 24(2):110-4.

PMID: 1577620 DOI: 10.1007/BF01082447.

An immunohistochemical study of human postnatal paraganglia associated with the urinary bladder.

Dixon J, Gosling J, Canning D, Gearhart J J Anat. 1992; 181 ( Pt 3):431-6.

PMID: 1304581 PMC: 1259696.

References

Hervonen A, Partanen S, Vaalasti A, Partanen M, Kanerva L, Alho H . The distribution and endocrine nature of the abdominal paraganglia of adult man. Am J Anat. 1978; 153(4):563-72. DOI: 10.1002/aja.1001530407. View

DeLellis R, Tischler A, Lee A, Blount M, WOLFE H . Leu-enkephalin-like immunoreactivity in proliferative lesions of the human adrenal medulla and extra-adrenal paraganglia. Am J Surg Pathol. 1983; 7(1):29-37. DOI: 10.1097/00000478-198301000-00003. View

Wharton J, Polak J, Pearse A, McGregor G, Bryant M, Bloom S . Enkephalin-, VIP- and substance P-like immunoreactivity in the carotid body. Nature. 1980; 284(5753):269-71. DOI: 10.1038/284269a0. View

Helen P, Alho H, Hervonen A . Ultrastructure and histochemistry of human SIF cells and paraganglia. Adv Biochem Psychopharmacol. 1980; 25:149-52. View

Linnoila R, DiAugustine R, Hervonen A, Miller R . Distribution of [Met5]- and [Leu5]-enkephalin-, vasoactive intestinal polypeptide- and substance P-like immunoreactivities in human adrenal glands. Neuroscience. 1980; 5(12):2247-59. DOI: 10.1016/0306-4522(80)90141-4. View

Schultzberg M, Hokfelt T, Terenius L, Elfvin L, Lundberg J, Brandt J . Enkephalin immunoreactive nerve fibres and cell bodies in sympathetic ganglia of the guinea-pig and rat. Neuroscience. 1979; 4(2):249-70. DOI: 10.1016/0306-4522(79)90087-3. View

Pelto-Huikko M, Salminen T, Hervonen A . Enkephalin-like immunoreactivity is restricted to the adrenaline cells in the hamster adrenal medulla. Histochemistry. 1982; 73(4):493-7. DOI: 10.1007/BF00493363. View

Lundberg J, Hamberger B, Schultzberg M, Hokfelt T, GRANBERG P, Efendic S . Enkephalin- and somatostatin-like immunoreactivities in human adrenal medulla and pheochromocytoma. Proc Natl Acad Sci U S A. 1979; 76(8):4079-83. PMC: 383981. DOI: 10.1073/pnas.76.8.4079. View

Viveros O, Diliberto Jr E, Hazum E, Chang K . Opiate-like materials in the adrenal medulla: evidence for storage and secretion with catecholamines. Mol Pharmacol. 1979; 16(3):1101-8. View

10.

Varndell I, Tapia F, de Mey J, Rush R, Bloom S, Polak J . Electron immunocytochemical localization of enkephalin-like material in catecholamine-containing cells of the carotid body, the adrenal medulla, and in pheochromocytomas of man and other mammals. J Histochem Cytochem. 1982; 30(7):682-90. DOI: 10.1177/30.7.6179985. View

11.

Hervonen A, Vaalasti A, VAALASTI T, Partanen M, Kanerva L . Paraganglia in the urogential tract of man. Histochemistry. 1976; 48(4):307-13. DOI: 10.1007/BF00499247. View

12.

Lundberg J, Hokfelt T, Fahrenkrug J, Nilsson G, Terenius L . Peptides in the cat carotid body (glomus caroticum): VIP-, enkephalin-, and substance P-like immunoreactivity. Acta Physiol Scand. 1979; 107(3):279-81. DOI: 10.1111/j.1748-1716.1979.tb06475.x. View

13.

Thompson S, Gosling J . Histochemical light microscopic study of catecholamine containing paraganglia in the human pelvis. Cell Tissue Res. 1976; 170(4):539-48. DOI: 10.1007/BF00361711. View

14.

Schultzberg M, Lundberg J, Hokfelt T, Terenius L, Brandt J, Elde R . Enkephalin-like immunoreactivity in gland cells and nerve terminals of the adrenal medulla. Neuroscience. 1978; 3(12):1169-86. DOI: 10.1016/0306-4522(78)90137-9. View

15.

Hervonen A, Pickel V, Joh T, Reis D, Linnoila I, Kanerva L . Immunocytochemical demonstration of the catecholamine-synthesizing enzymes and neuropeptides in the catecholamine-storing cells of human fetal sympathetic nervous system. Adv Biochem Psychopharmacol. 1980; 25:373-8. View

16.

Hervonen A . Development of catecholamine--storing cells in human fetal paraganglia and adrenal medulla. A histochemical and electron microscopical study. Acta Physiol Scand Suppl. 1971; 368:1-94. View

17.

Pickel V, Joh T, Reis D, Leeman S, Miller R . Electron microscopic localization of substance P and enkephalin in axon terminals related to dendrites of catecholaminergic neurons. Brain Res. 1979; 160(3):387-400. DOI: 10.1016/0006-8993(79)91068-0. View

18.

Viveros O, Diliberto Jr E, Hazum E, Chang K . Enkephalins as possible adrenomedullary hormones: storage, secretion, and regulation of synthesis. Adv Biochem Psychopharmacol. 1980; 22:191-204. View

19.

Kobayashi S, Uchida T, Ohashi T, Fujita T, Nakao K, Yoshimasa T . Immunocytochemical demonstration of the co-storage of noradrenaline with Met-enkephalin-Arg6-Phe7 and Met-enkephalin-Arg6-Gly7-Leu8 in the carotid body chief cells of the dog. Arch Histol Jpn. 1983; 46(5):713-22. DOI: 10.1679/aohc.46.713. View