Pathogenesis of Lupus Dermatoses in Autoimmune Mice. IV. Association Between Cutaneous Immunoglobulin Deposition and Anti-single-stranded DNA Antibodies in Sera

Overview

Journal Arch Dermatol Res

Specialty Dermatology

Date 1985 Jan 1

PMID 3885874

Citations 5

Authors

F Furukawa

A Kohno

G Ohshio

K Suzuki

Y Hamashima

Affiliations

Soon will be listed here.

Abstract

The skin of New Zealand, MRL and BXSB mice was immunohistopathologically examined in order to study the appearance of skin immunoglobulin (Ig) deposition and its correlation with the occurrence of anti-single-stranded (ss) DNA antibodies in sera. Our studies revealed Ig deposition at the dermoepidermal junction (DEJ) in non-lesional skin and a significant age-related correlation between skin Ig deposition and serum anti-ssDNA antibodies. However, immunofluorescent study of autoimmune mice using anti-ultraviolet-irradiated DNA antiserum failed to demonstrate DNA antigens at the DEJ.

Citing Articles

Pathogenesis of lupus dermatoses in autoimmune mice. XIX. Attempts to induce subepidermal immunoglobulin deposition in MRL/Mp- +/+ mice.

Furukawa F, Ohshio G, Imamura S Arch Dermatol Res. 1993; 285(1-2):20-6.

PMID: 8470930 DOI: 10.1007/BF00370818.

Histamine metabolism in skin of MRL/l mice.

Tachibana T, Furukawa F, Taniguchi S, Hamashima Y, Imamura S Arch Dermatol Res. 1985; 278(1):57-60.

PMID: 4096531 DOI: 10.1007/BF00412497.

Pathogenesis of lupus dermatoses in autoimmune mice. VI. Correlation between positivity of lupus band test and lupus nephritis.

Furukawa F, Ohshio G, Tanaka H, Nakamura T, Ikehara S, Imamura S Arch Dermatol Res. 1986; 278(4):343-6.

PMID: 3827991 DOI: 10.1007/BF00407752.

Ultrastructural lupus band test in the skin of MRL mice.

Horiguchi Y, Furukawa F, Hamashima Y, Imamura S Arch Dermatol Res. 1986; 278(6):474-80.

PMID: 3539034 DOI: 10.1007/BF00455167.

Effects of ultraviolet light irradiation on the skin of MRL/l mice.

Horiguchi Y, Furukawa F, Ohshio G, Horio T, Imamura S Arch Dermatol Res. 1987; 279(7):478-83.

PMID: 3435176 DOI: 10.1007/BF00412595.

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