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Comparison of 1 Versus 2 Doses of Quadrivalent Influenza Vaccine in 3-8-Year-Old Children with Different Immunological States - Jiangsu Province, China, 2021

Overview
Journal China CDC Wkly
Date 2024 Jun 10
PMID 38854751
Authors
Qian Liu
Pengfei Jin
Jingxin Li
Xiaoqin Chen
Chenhao Wang
Qingbin Lu
Wei Jiang
Shixuan Zhang
Lairun Jin
Hongxin Pan
Xue Guo
Fengcai Zhu
Affiliations
Soon will be listed here.
Abstract

What Is Already Known About This Topic?: The quadrivalent influenza vaccine (QIV) provides protection against a broader range of influenza strains by including strains of influenza A/H1N1, A/H3N2, B/Yamagata, and B/Victoria.

What Is Added By This Report?: This study aimed to assess the immunogenicity and safety of administering a single dose compared to two doses of QIV in children, taking into consideration their previous influenza vaccination history.

What Are The Implications For Public Health Practice?: This study provides evidence supporting the use of a single dose of the QIV in children aged 3-8 years who have previously received two or more doses of influenza vaccine. However, children who have not been previously vaccinated with influenza vaccine should still adhere to the recommended schedule of receiving two doses.

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