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[Frequency of Delta Infections in Heidelberg]

Overview
Journal Klin Wochenschr
Specialty General Medicine
Date 1985 Feb 15
PMID 3884893
Authors
K Gmelin
L Theilmann
M Roggendorf
P Wolf
U Schlipkoter
P Czygan
B KOMMERELL
F Deinhardt
Affiliations
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Abstract

The frequency of delta infection was studied in sera of 203 patients with acute hepatitis B, further 461 hepatitis B virus surface antigen-(HBsAg)-positive patients and 117 HBsAg-negative controls by determination of anti-delta by a competitive enzyme immunoassay. Sera have been collected since 1974. None of the sera of acute hepatitis B was anti-delta-positive whereas seven of the HBsAg-positive carriers were anti-delta-positive. Two of the anti-delta-positive patients had chronic hepatitis, four had liver cirrhosis. One of the anti-delta-positive patients with liver cirrhosis died of liver failure. Risk factors included Italian origin and parenteral routes of infection. All sera of 19 relatives of three anti-delta-positive index cases remained anti-delta-negative.

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