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Association Between High-risk Fertility Behaviors and Neonatal Mortality in Ethiopia: A Multilevel Mixed-effects Logit Models from 2019 Ethiopian Mini Demographic and Health Survey

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Date 2024 Jun 7
PMID 38846107
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Abstract

Objectives: This study aimed to explore the association between high-risk fertility behaviors and neonatal mortality in Ethiopia.

Study Design: A community-based cross-sectional study was conducted using data from the 2019 Ethiopian Mini-Demographic and Health Survey.

Methods: Mixed-effects logit regression models were fitted to 5527 children nested within 305 clusters. The definition of high-risk fertility behavior was adopted from the 2019 EMDHS. The fixed effects (the association between the outcome variable and the explanatory variables) were expressed as adjusted odds ratios (ORs) with 95 % confidence intervals and measures of variation explained by intra-class correlation coefficients, median odds ratio, and proportional change invariance.

Results: The presence of births with any multiple high-risk fertility behaviors was associated with a 70 % higher risk of neonatal mortality (AOR = 1.7, (95 % CI: 1.2, 2.3) than those with no high-risk fertility behavior. From the combined risks of high-risk fertility behaviors, the combination of preceding birth interval <24 months and birth order four or higher had an 80 % increased risk of neonatal mortality (AOR = 1.8, (95 % CI, 1.2, 2.7) as compared to those who did not have either of the two. The 3-way risks (combination of preceding birth interval <24 months, birth order 4+, and mother's age at birth 34+) were associated with approximately four times increased odds of neonatal mortality (AOR (95 % CI:3.9 (2.1, 7.4)].

Conclusions: High-risk fertility behavior is a critical predictor of neonatal mortality in Ethiopia, with three-way high-risk fertility behaviors increasing the risk of neonatal mortality fourfold. In addition, antenatal follow-up was the only non-high fertility behavioral factor significantly associated with the risk of neonatal mortality in Ethiopia.

References
1.
Alebel A, Wagnew F, Petrucka P, Tesema C, Moges N, Ketema D . Neonatal mortality in the neonatal intensive care unit of Debre Markos referral hospital, Northwest Ethiopia: a prospective cohort study. BMC Pediatr. 2020; 20(1):72. PMC: 7023807. DOI: 10.1186/s12887-020-1963-z. View

2.
Tessema Z, Tamirat K . Determinants of high-risk fertility behavior among reproductive-age women in Ethiopia using the recent Ethiopian Demographic Health Survey: a multilevel analysis. Trop Med Health. 2020; 48(1):93. PMC: 7697365. DOI: 10.1186/s41182-020-00280-1. View

3.
Hug L, Alexander M, You D, Alkema L . National, regional, and global levels and trends in neonatal mortality between 1990 and 2017, with scenario-based projections to 2030: a systematic analysis. Lancet Glob Health. 2019; 7(6):e710-e720. PMC: 6527519. DOI: 10.1016/S2214-109X(19)30163-9. View

4.
Tewabe T, Mehariw Y, Negatie E, Yibeltal B . Neonatal mortality in the case of Felege Hiwot referral hospital, Bahir Dar, Amhara Regional State, North West Ethiopia 2016: a one year retrospective chart review. Ital J Pediatr. 2018; 44(1):57. PMC: 5963133. DOI: 10.1186/s13052-018-0498-5. View

5.
Conde-Agudelo A, Rosas-Bermudez A, Castano F, Norton M . Effects of birth spacing on maternal, perinatal, infant, and child health: a systematic review of causal mechanisms. Stud Fam Plann. 2012; 43(2):93-114. DOI: 10.1111/j.1728-4465.2012.00308.x. View