Ammonia As an Indicator of Exercise Stress Implications of Recent Findings to Sports Medicine

Overview

Journal Sports Med

Specialty Orthopedics

Date 1985 Jan 1

PMID 3883458

Citations 8

Authors

E W BANISTER

W Rajendra

B J Mutch

Affiliations

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Abstract

The role of ammonia in exercise-induced fatigue is reviewed. Implications for integrated activity of developing hyperammoneic states, caused by various precipitating conditions such as exercise, liver dysfunction, hypoxia, hyperoxia, and chemical poisoning are described. The central role of ammonia in diverse important metabolic pathways indicates its ubiquitous role in a spectrum of activity ranging from elite exhaustive performance of sportsmen and -women to life-threatening organ dysfunction. The action of ammonia and metabolites from associated pathways in producing seemingly dangerous short term conditions, but inducing possible long term protection against degenerative processes associated with ageing (free radical-induced cellular damage) indicate the paradoxical position of ammonia and its associated metabolic pathways for health and disease processes.

Citing Articles

Low-Dose Ammonium Preconditioning Enhances Endurance in Submaximal Physical Exercises.

Mindukshev I, Sudnitsyna J, Goncharov N, Skverchinskaya E, Dobrylko I, Nikitina E Sports (Basel). 2021; 9(2).

PMID: 33669436 PMC: 7920466. DOI: 10.3390/sports9020029.

Resistance exercise overtraining and overreaching. Neuroendocrine responses.

Fry A, Kraemer W Sports Med. 1997; 23(2):106-29.

PMID: 9068095 DOI: 10.2165/00007256-199723020-00004.

Amino acid metabolism in tennis and its possible influence on the neuroendocrine system.

Struder H, Hollmann W, Duperly J, Weber K Br J Sports Med. 1995; 29(1):28-30.

PMID: 7788213 PMC: 1332214. DOI: 10.1136/bjsm.29.1.28.

Influence of peripheral arterial occlusive disease on muscular metabolism. Part 2: Changes in pyruvate, alanine, and urea concentration in femoral blood.

Rexroth W, Isgro F, Koeth T, Manzl G, WEICKER H Klin Wochenschr. 1989; 67(12):616-20.

PMID: 2770179 DOI: 10.1007/BF01718142.

Influence of peripheral arterial occlusive disease on muscular metabolism. Part 1: Changes in lactate, ammonia, and hypoxanthine concentration in femoral blood.

Rexroth W, Hageloch W, Isgro F, Koeth T, Manzl G, WEICKER H Klin Wochenschr. 1989; 67(11):576-82.

PMID: 2747135 DOI: 10.1007/BF01721684.

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