» Articles » PMID: 38830619

Adult Obesity Treatment and Prevention: A Trans-agency Commentary on the Research Landscape, Gaps, and Future Opportunities

Abstract

Given the high and growing prevalence of obesity among adults in the United States, obesity treatment and prevention are important topics in biomedical and public health research. Although researchers recognize the significance of this problem, much remains unknown about safe and effective prevention and treatment of obesity in adults. In response to the worsening obesity epidemic and the many unknowns regarding the disease, a group of key scientific and program staff members of the National Institutes of Health (NIH) and other federal and non-government agencies gathered virtually in September 2021 to discuss the current state of obesity research, research gaps, and opportunities for future research in adult obesity prevention and treatment. The current article synthesizes presentations given by attendees and shares their organizations' current initiatives and identified gaps and opportunities. By integrating the information discussed in the meeting and current initiatives, we identify potential targets and overlapping priorities for future research, including health equity and disparities in obesity, the heterogeneity of obesity, and the use of technological and innovative approaches in interventions.

References
1.
Olson R, Wipfli B, Thompson S, Elliot D, Anger W, Bodner T . Weight Control Intervention for Truck Drivers: The SHIFT Randomized Controlled Trial, United States. Am J Public Health. 2016; 106(9):1698-706. PMC: 4981787. DOI: 10.2105/AJPH.2016.303262. View

2.
Simmonds M, Llewellyn A, Owen C, Woolacott N . Predicting adult obesity from childhood obesity: a systematic review and meta-analysis. Obes Rev. 2015; 17(2):95-107. DOI: 10.1111/obr.12334. View

3.
Chang S, Yu Y, Carlsson N, Liu X, Colditz G . Racial disparity in life expectancies and life years lost associated with multiple obesity-related chronic conditions. Obesity (Silver Spring). 2017; 25(5):950-957. PMC: 5404943. DOI: 10.1002/oby.21822. View

4.
Wearing S, Hennig E, Byrne N, Steele J, Hills A . Musculoskeletal disorders associated with obesity: a biomechanical perspective. Obes Rev. 2006; 7(3):239-50. DOI: 10.1111/j.1467-789X.2006.00251.x. View

5.
Messier S, Beavers D, Queen K, Mihalko S, Miller G, Losina E . Effect of Diet and Exercise on Knee Pain in Patients With Osteoarthritis and Overweight or Obesity: A Randomized Clinical Trial. JAMA. 2022; 328(22):2242-2251. PMC: 9856237. DOI: 10.1001/jama.2022.21893. View