Biological Clock Regulation by the Gene Family: a New Perspective on Tumor Development

Overview

Journal Front Cell Dev Biol

Specialty Cell Biology

Date 2024 May 30

PMID 38813085

Authors

Kai Chen

Yaohui Wang

Dengxiong Li

Ruicheng Wu

Jie Wang

Wuran Wei

Wei Zhu

Wenhua Xie

Dechao Feng

Yi He

Affiliations

Soon will be listed here.

Abstract

The Period () gene family is one of the core components of the circadian clock, with substantial correlations between the genes and cancers identified in extensive researches. Abnormal mutations in genes can influence cell function, metabolic activity, immunity, and therapy responses, thereby promoting the initiation and development of cancers. This ultimately results in unequal cancers progression and prognosis in patients. This leads to variable cancer progression and prognosis among patients. In-depth studies on the interactions between the genes and cancers can reveal novel strategies for cancer detection and treatment. In this review, we aim to provide a comprehensive overview of the latest research on the role of the gene family in cancer.

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