Repeated Ischemic Stroke Due to in Situ Thrombus at the Middle Cerebral Artery in a Patient with Essential Thrombocythemia

Overview

Journal Intern Med

Specialty General Medicine

Date 2024 May 29

PMID 38811226

Authors

Toru Nakagami

Yuji Kato

Kaito Watanabe

Ryutaro Kimura

Tsugumi Sato

Takeshi Hayashi

Satoshi Suda

Affiliations

Soon will be listed here.

Abstract

Essential thrombocythemia (ET) is a myeloproliferative neoplasm that is a rare cause of ischemic stroke. We herein report a 70-year-old man with JAK2 V617F mutation-positive ET who experienced ischemic stroke twice in 1 month due to transient stenosis. In both events, transient stenosis formed at the same curvature of the right middle cerebral artery, and the thrombus disappeared with the initiation of antiplatelet agents. The formation of in situ thrombus at the curvature of the intracranial vessels may be a unique characteristic of JAK2 V617F mutation-positive ET patients.

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