Infection of Transcatheter Valvular Devices

Overview

Journal Curr Cardiol Rep

Publisher Current Science

Specialty Cardiology & Vascular Diseases

Date 2024 May 28

PMID 38806975

Authors

Taha Hatab

Syed Zaid

Samarthkumar J Thakkar

Rody G Bou Chaaya

Sachin S Goel

Michael J Reardon

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: This review explores the epidemiology, clinical traits, and diagnosis of Transcatheter Aortic Valve Replacement-Associated Infective Endocarditis (TAVR-IE) and mitral transcatheter edge-to-edge repair infective endocarditis (TEER-IE), focusing on a multimodal imaging approach. It addresses the rising prevalence of TAVR and TEER, emphasizing the need to understand long-term complications and clinical consequences, which poses significant challenges despite advancements in valve technology.

Recent Findings: Studies report a variable incidence of TAVR-IE and TEER-IE influenced by diverse patient risk profiles and procedural factors. Younger age, male gender, and certain comorbidities emerge as patient-related risk factors. Procedure-related factors include intervention location, valve type, and technical aspects. Microbiologically, Staphylococcus aureus, Viridans Group Streptococcus, and Enterococcus are frequently encountered pathogens. TAVR-IE and TEER-IE diagnosis involves a multimodal imaging approach due to limitations in echocardiography. Blood cultures and imaging aid identification, with Fluorescence in situ hybridization is showing promise. Treatment encompasses medical management with antibiotics and, when necessary, surgical intervention. The management approach requires a multidisciplinary "Endocarditis Team." This review underscores the need for continued research to refine risk prediction, enhance diagnostic accuracy, and optimize management strategies for TAVR-IE, considering the evolving landscape of transcatheter interventions.

References

Leon M, Smith C, Mack M, Miller D, Moses J, Svensson L . Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med. 2010; 363(17):1597-607. DOI: 10.1056/NEJMoa1008232. View

Mack M, Leon M, Thourani V, Makkar R, Kodali S, Russo M . Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients. N Engl J Med. 2019; 380(18):1695-1705. DOI: 10.1056/NEJMoa1814052. View

Popma J, Adams D, Reardon M, Yakubov S, Kleiman N, Heimansohn D . Transcatheter aortic valve replacement using a self-expanding bioprosthesis in patients with severe aortic stenosis at extreme risk for surgery. J Am Coll Cardiol. 2014; 63(19):1972-81. DOI: 10.1016/j.jacc.2014.02.556. View

Reardon M, Van Mieghem N, Popma J, Kleiman N, Sondergaard L, Mumtaz M . Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients. N Engl J Med. 2017; 376(14):1321-1331. DOI: 10.1056/NEJMoa1700456. View

Nishimura R, Otto C, Bonow R, Carabello B, Erwin 3rd J, Fleisher L . 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017; 135(25):e1159-e1195. DOI: 10.1161/CIR.0000000000000503. View

Regueiro A, Linke A, Latib A, Ihlemann N, Urena M, Walther T . Association Between Transcatheter Aortic Valve Replacement and Subsequent Infective Endocarditis and In-Hospital Death. JAMA. 2016; 316(10):1083-92. DOI: 10.1001/jama.2016.12347. View

Del Val D, Panagides V, Mestres C, Miro J, Rodes-Cabau J . Infective Endocarditis After Transcatheter Aortic Valve Replacement: JACC State-of-the-Art Review. J Am Coll Cardiol. 2023; 81(4):394-412. DOI: 10.1016/j.jacc.2022.11.028. View

Amat-Santos I, Messika-Zeitoun D, Eltchaninoff H, Kapadia S, Lerakis S, Cheema A . Infective endocarditis after transcatheter aortic valve implantation: results from a large multicenter registry. Circulation. 2015; 131(18):1566-74. DOI: 10.1161/CIRCULATIONAHA.114.014089. View

Butt J, Ihlemann N, De Backer O, Sondergaard L, Havers-Borgersen E, Gislason G . Long-Term Risk of Infective Endocarditis After Transcatheter Aortic Valve Replacement. J Am Coll Cardiol. 2019; 73(13):1646-1655. DOI: 10.1016/j.jacc.2018.12.078. View

10.

Regueiro A, Linke A, Latib A, Ihlemann N, Urena M, Walther T . Infective Endocarditis Following Transcatheter Aortic Valve Replacement: Comparison of Balloon- Versus Self-Expandable Valves. Circ Cardiovasc Interv. 2019; 12(11):e007938. DOI: 10.1161/CIRCINTERVENTIONS.119.007938. View

11.

Moriyama N, Laakso T, Biancari F, Raivio P, Jalava M, Jaakkola J . Prosthetic valve endocarditis after transcatheter or surgical aortic valve replacement with a bioprosthesis: results from the FinnValve Registry. EuroIntervention. 2019; 15(6):e500-e507. DOI: 10.4244/EIJ-D-19-00247. View

12.

Summers M, Leon M, Smith C, Kodali S, Thourani V, Herrmann H . Prosthetic Valve Endocarditis After TAVR and SAVR: Insights From the PARTNER Trials. Circulation. 2019; 140(24):1984-1994. DOI: 10.1161/CIRCULATIONAHA.119.041399. View

13.

Stone G, Weissman N, Mack M . Transcatheter Mitral-Valve Repair in Patients with Heart Failure. Reply. N Engl J Med. 2019; 380(20):1980-1981. DOI: 10.1056/NEJMc1903982. View

14.

Otto C, Nishimura R, Bonow R, Carabello B, Erwin 3rd J, Gentile F . 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2020; 143(5):e35-e71. DOI: 10.1161/CIR.0000000000000932. View

15.

Saito S, Baraki H, Fleischer B, Kutschka I . Mitral valve replacement after failed MitraClip™ therapy: report of two cases. J Artif Organs. 2014; 18(2):177-80. DOI: 10.1007/s10047-014-0814-9. View

16.

Nicolo F, Scrofani R, Antona C . Bartonella haenselae infective endocarditis following transcatheter edge-to-edge mitral valve repair: A case report. J Card Surg. 2019; 34(6):514-517. DOI: 10.1111/jocs.14047. View

17.

Cahill T, Raby J, Jewell P, Brennan P, Banning A, Byrne J . Risk of infective endocarditis after surgical and transcatheter aortic valve replacement. Heart. 2022; 108(8):639-647. DOI: 10.1136/heartjnl-2021-320080. View

18.

Fauchier L, Bisson A, Herbert J, Lacour T, Bourguignon T, Etienne C . Incidence and outcomes of infective endocarditis after transcatheter aortic valve implantation versus surgical aortic valve replacement. Clin Microbiol Infect. 2020; 26(10):1368-1374. DOI: 10.1016/j.cmi.2020.01.036. View

19.

Del Val D, Abdel-Wahab M, Linke A, Durand E, Ihlemann N, Urena M . Temporal Trends, Characteristics, and Outcomes of Infective Endocarditis After Transcatheter Aortic Valve Replacement. Clin Infect Dis. 2021; 73(11):e3750-e3758. DOI: 10.1093/cid/ciaa1941. View

20.

Stortecky S, Heg D, Tueller D, Pilgrim T, Muller O, Noble S . Infective Endocarditis After Transcatheter Aortic Valve Replacement. J Am Coll Cardiol. 2020; 75(24):3020-3030. DOI: 10.1016/j.jacc.2020.04.044. View