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Evaluation of Steroid-Induced Osteoporosis Prevention Using Tracing Reports in Collaboration Between Hospitals and Community Pharmacists

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Date 2024 May 28
PMID 38804472
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Abstract

Glucocorticoid-induced osteoporosis (GIOP) is a side effect of glucocorticoid (GC) treatment; however, despite established prevention guidelines in various countries, a gap persists between these guidelines and clinical practice. To address this gap, we implemented a collaborative intervention between hospitals and community pharmacists, aiming to assess its effectiveness. Pharmacists recommended to the prescribing doctor osteoporosis treatment for patients who did not undergo osteoporosis treatment with a fracture risk score of ≥3 via tracing reports (TRs), between 15 December 2021, and 21 January 2022. Data were extracted from electronic medical records, including prescriptions, concomitant medications, reasons for not pursuing osteoporosis treatment, and TR contents. Of 391 evaluated patients, 45 were eligible for TRs, with 34 (75.6%) being males. Prednisolone was the most common GCs administered, and urology was the predominant treatment department. Among the 45 patients who received TRs, prescription suggestions were accepted for 19 (42.2%). After undertaking the intervention, guideline adherence significantly increased from 87% to 92.5%. This improvement indicates that TRs effectively bridged the evidence-practice gap in GIOP prevention among GC patients, suggesting their potential utility. Expansion of this initiative is warranted to further prevent GIOP.

References
1.
Naunton M, Peterson G, Jones G, Griffin G, Bleasel M . Multifaceted educational program increases prescribing of preventive medication for corticosteroid induced osteoporosis. J Rheumatol. 2004; 31(3):550-6. View

2.
van Staa T, Laan R, Barton I, Cohen S, Reid D, Cooper C . Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy. Arthritis Rheum. 2003; 48(11):3224-9. DOI: 10.1002/art.11283. View

3.
Laurent M, Goemaere S, Verroken C, Bergmann P, Body J, Bruyere O . Prevention and Treatment of Glucocorticoid-Induced Osteoporosis in Adults: Consensus Recommendations From the Belgian Bone Club. Front Endocrinol (Lausanne). 2022; 13:908727. PMC: 9219603. DOI: 10.3389/fendo.2022.908727. View

4.
Buckley L, Guyatt G, Fink H, Cannon M, Grossman J, Hansen K . 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Arthritis Rheumatol. 2017; 69(8):1521-1537. DOI: 10.1002/art.40137. View

5.
Soen S, Kaku M, Okubo N, Touzeni S, Saito K, Kobayashi M . Epidemiology of glucocorticoid-induced osteoporosis and management of associated fracture risk in Japan. J Bone Miner Metab. 2021; 39(6):1019-1030. DOI: 10.1007/s00774-021-01236-z. View