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Should Major Trauma Fractures Be Part of a Fracture Liaison Service's Remit: a Cost-benefit Estimate

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Journal Osteoporos Int
Date 2024 May 27
PMID 38802556
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Abstract

Purpose: To compare the 3-year refracture rate following minimal trauma (MT) and non-minimal trauma (non-MT) injuries and evaluate the cost of extending fracture liaison service (FLS) operations to non-MT presentations.

Methods: Patients aged 50, or above presenting to the John Hunter Hospital with a fracture in calendar year 2018 were identified through the Integrated Patient Management System (IPMS) of the Hunter New England Health Service's (HNEHS), and re-presentation to any HNEHS facility over the following 3 years monitored. The refracture rate of MT and non-MT presentations was compared and analysed using Cox proportional hazards regression models. The cost of including non-MT patients was estimated through the use of a previously conducted micro-costing analysis. The operational fidelity of the FLS to the previous estimate was confirmed by comparing the 3-year refracture rate of MT presentations in the two studies.

Results: The 3-year refracture rate following a MT injury was 8% and after non-MT injury 4.5%. Extension of FLS activities to include non-MT patients in 2022 would have cost an additional $198,326 AUD with a notional loss/saving of $ - 26,625/ + 26,913 AUD through refracture risk reduction. No clinically available characteristic at presentation predictive of increased refracture risk was identified.

Conclusion: The 3-year refracture after a non-MT injury is about half (57%) that of the refracture rate after a MT injury. Extending FLS activity to non-MT patients incurs a significant additional direct cost but remains cost neutral if notional savings gained through reduction in refracture risk are taken into account.

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References
1.
Van der Kallen J, Giles M, Cooper K, Gill K, Parker V, Tembo A . A fracture prevention service reduces further fractures two years after incident minimal trauma fracture. Int J Rheum Dis. 2014; 17(2):195-203. DOI: 10.1111/1756-185X.12101. View

2.
Center J, Bliuc D, Nguyen T, Eisman J . Risk of subsequent fracture after low-trauma fracture in men and women. JAMA. 2007; 297(4):387-94. DOI: 10.1001/jama.297.4.387. View

3.
Sanders K, Pasco J, Ugoni A, Nicholson G, Seeman E, Martin T . The exclusion of high trauma fractures may underestimate the prevalence of bone fragility fractures in the community: the Geelong Osteoporosis Study. J Bone Miner Res. 1998; 13(8):1337-42. DOI: 10.1359/jbmr.1998.13.8.1337. View

4.
Nolan E, Chen H . A comparison of the Cox model to the Fine-Gray model for survival analyses of re-fracture rates. Arch Osteoporos. 2020; 15(1):86. DOI: 10.1007/s11657-020-00748-x. View

5.
Nakayama A, Major G, Holliday E, Attia J, Bogduk N . Evidence of effectiveness of a fracture liaison service to reduce the re-fracture rate. Osteoporos Int. 2015; 27(3):873-879. PMC: 4767862. DOI: 10.1007/s00198-015-3443-0. View