The Change of Symptom Clusters in Gastric Cancer Patients During the Perioperative Period: a Longitudinal Study

Overview

Journal Support Care Cancer

Specialties Critical Care
Oncology

Date 2024 May 27

PMID 38801426

Authors

Jianjian Wei

Hongxia Yan

Wen Yin

Fang He

Affiliations

Soon will be listed here.

Abstract

Aim And Objectives: The purpose of this study was to describe the number, type and trajectory of symptom clusters during the perioperative period in patients with gastric cancer at four different time points. The study also aimed to identify the changes and consistency of these symptom clusters over time.

Design: This was a longitudinal study.

Methods: This study was conducted in a tertiary cancer hospital with 205 patients with gastric cancer. The M.D. Anderson Symptom Inventory Gastrointestinal Cancer Module was used to assess the incidence and severity of symptom clusters. Exploratory factor analysis was used to extract symptom clusters.

Results: The study identified four symptom clusters in patients with gastric cancer during the perioperative period: gastrointestinal symptom cluster, physical symptom cluster, psychological symptom cluster, and sleep disturbance symptom cluster. These clusters were observed across two to four time points.

Conclusion: The findings of this study provide scientific evidence for medical staff and researchers to better understand the symptoms of patients with gastrointestinal cancer during the perioperative period. These findings can help develop individualized interventions for managing symptoms.

Relevance To Clinical Practice: Gastric cancer patients suffered from various symptom clusters, which lasted from one day before surgery to one month after surgery. They should be given careful consideration by clinical staff.

References

Sung H, Ferlay J, Siegel R, Laversanne M, Soerjomataram I, Jemal A . Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021; 71(3):209-249. DOI: 10.3322/caac.21660. View

Lin Y, Docherty S, Porter L, Bailey D . Common and Co-Occurring Symptoms Experienced by Patients With Gastric Cancer. Oncol Nurs Forum. 2020; 47(2):187-202. DOI: 10.1188/20.ONF.187-202. View

Dodd M, Miaskowski C, Paul S . Symptom clusters and their effect on the functional status of patients with cancer. Oncol Nurs Forum. 2001; 28(3):465-70. View

Wang X, Wang Y, Guo H, Mendoza T, Hao X, Cleeland C . Chinese version of the M. D. Anderson Symptom Inventory: validation and application of symptom measurement in cancer patients. Cancer. 2004; 101(8):1890-901. DOI: 10.1002/cncr.20448. View

Kim H, McGuire D, Tulman L, Barsevick A . Symptom clusters: concept analysis and clinical implications for cancer nursing. Cancer Nurs. 2005; 28(4):270-82. DOI: 10.1097/00002820-200507000-00005. View

Kim G, Kim S, Song S, Kim H, Kang B, Noh S . Prevalence and prognostic implications of psychological distress in patients with gastric cancer. BMC Cancer. 2017; 17(1):283. PMC: 5399416. DOI: 10.1186/s12885-017-3260-2. View

Climent M, Munarriz M, Blazeby J, Dorcaratto D, Ramon J, Carrera M . Weight loss and quality of life in patients surviving 2 years after gastric cancer resection. Eur J Surg Oncol. 2017; 43(7):1337-1343. DOI: 10.1016/j.ejso.2017.01.239. View

Oh H, Choi M, Park J, Song K, Yoo H . Acid Secretion and Its Relationship to Esophageal Reflux Symptom in Patients with Subtotal Gastrectomy. Dig Dis Sci. 2018; 63(3):703-712. DOI: 10.1007/s10620-018-4923-9. View

Shim E, Noh H, Lee K, Hwang H, Son K, Jung D . Trajectory of severity of postoperative delirium symptoms and its prospective association with cognitive function in patients with gastric cancer: results from a prospective observational study. Support Care Cancer. 2019; 27(8):2999-3006. DOI: 10.1007/s00520-018-4604-4. View

10.

Cleeland C, Mendoza T, Wang X, Chou C, Harle M, Morrissey M . Assessing symptom distress in cancer patients: the M.D. Anderson Symptom Inventory. Cancer. 2000; 89(7):1634-46. DOI: 10.1002/1097-0142(20001001)89:7<1634::aid-cncr29>3.0.co;2-v. View

11.

Li J, Li J, Wu J, Song Y, Hu S, Hong J . Change in symptom clusters perioperatively in patients with lung cancer. Eur J Oncol Nurs. 2021; 55:102046. DOI: 10.1016/j.ejon.2021.102046. View

12.

Chen R, Yang S, Xu Z, Peng M, Chen M, Wang Q . Validation and Application of the Chinese Version of the M. D. Anderson Symptom Inventory Gastrointestinal Cancer Module (MDASI-GI-C). J Pain Symptom Manage. 2019; 57(4):820-827. DOI: 10.1016/j.jpainsymman.2019.01.007. View

13.

Russell J, Wong M, Mackin L, Paul S, Cooper B, Hammer M . Stability of Symptom Clusters in Patients With Lung Cancer Receiving Chemotherapy. J Pain Symptom Manage. 2019; 57(5):909-922. PMC: 6486424. DOI: 10.1016/j.jpainsymman.2019.02.002. View

14.

Kim H, Barsevick A, Tulman L, McDermott P . Treatment-related symptom clusters in breast cancer: a secondary analysis. J Pain Symptom Manage. 2008; 36(5):468-79. DOI: 10.1016/j.jpainsymman.2007.11.011. View

16.

Fu L, Feng X, Jin Y, Lu Z, Li R, Xu W . Symptom Clusters and Quality of Life in Gastric Cancer Patients Receiving Chemotherapy. J Pain Symptom Manage. 2021; 63(2):230-243. DOI: 10.1016/j.jpainsymman.2021.09.003. View

17.

Hammer M, Cooper B, Paul S, Kober K, Cartwright F, Conley Y . Identification of Distinct Symptom Profiles in Cancer Patients Using a Pre-Specified Symptom Cluster. J Pain Symptom Manage. 2022; 64(1):17-27. DOI: 10.1016/j.jpainsymman.2022.03.007. View

18.

Sullivan C, Leutwyler H, Dunn L, Cooper B, Paul S, Levine J . Stability of Symptom Clusters in Patients With Breast Cancer Receiving Chemotherapy. J Pain Symptom Manage. 2017; 55(1):39-55. PMC: 5734998. DOI: 10.1016/j.jpainsymman.2017.08.008. View

19.

Pozzar R, Hammer M, Cooper B, Kober K, Chen L, Paul S . Stability of Symptom Clusters in Patients With Gynecologic Cancer Receiving Chemotherapy. Cancer Nurs. 2021; 45(4):E706-E718. PMC: 8940749. DOI: 10.1097/NCC.0000000000000988. View

20.

Smith J, Smith M . Does a preoperative bowel preparation reduce bowel morbidity and length of stay after scoliosis surgery? A randomized prospective study. J Pediatr Orthop. 2013; 33(8):e69-71. DOI: 10.1097/BPO.0b013e318296e032. View

21.

Han C, Reding K, Cooper B, Paul S, Conley Y, Hammer M . Symptom Clusters in Patients With Gastrointestinal Cancers Using Different Dimensions of the Symptom Experience. J Pain Symptom Manage. 2019; 58(2):224-234. PMC: 6679763. DOI: 10.1016/j.jpainsymman.2019.04.035. View