» Articles » PMID: 38800466

FiNN: A Toolbox for Neurophysiological Network Analysis

Overview
Journal Netw Neurosci
Publisher MIT Press
Specialty Neurology
Date 2024 May 27
PMID 38800466
Authors
Affiliations
Soon will be listed here.
Abstract

Recently, neuroscience has seen a shift from localist approaches to network-wide investigations of brain function. Neurophysiological signals across different spatial and temporal scales provide insight into neural communication. However, additional methodological considerations arise when investigating network-wide brain dynamics rather than local effects. Specifically, larger amounts of data, investigated across a higher dimensional space, are necessary. Here, we present FiNN (nd europhysiological etworks), a novel toolbox for the analysis of neurophysiological data with a focus on functional and effective connectivity. FiNN provides a wide range of data processing methods and statistical and visualization tools to facilitate inspection of connectivity estimates and the resulting metrics of brain dynamics. The Python toolbox and its documentation are freely available as Supporting Information. We evaluated FiNN against a number of established frameworks on both a conceptual and an implementation level. We found FiNN to require much less processing time and memory than other toolboxes. In addition, FiNN adheres to a design philosophy of easy access and modifiability, while providing efficient data processing implementations. Since the investigation of network-level neural dynamics is experiencing increasing interest, we place FiNN at the disposal of the neuroscientific community as open-source software.

Citing Articles

Dynamic mechanisms that couple the brain and breathing to the external environment.

Goheen J, Wolman A, Angeletti L, Wolff A, Anderson J, Northoff G Commun Biol. 2024; 7(1):938.

PMID: 39097670 PMC: 11297933. DOI: 10.1038/s42003-024-06642-3.


Oscillatory network markers of subcallosal cingulate deep brain stimulation for depression.

Scherer M, Harmsen I, Samuel N, Elias G, Germann J, Boutet A Brain Stimul. 2023; 16(6):1764-1775.

PMID: 38061548 PMC: 10947774. DOI: 10.1016/j.brs.2023.11.016.


Unique Brain Network Identification Number for Parkinson's and Healthy Individuals Using Structural MRI.

Samantaray T, Gupta U, Saini J, Gupta C Brain Sci. 2023; 13(9).

PMID: 37759898 PMC: 10526827. DOI: 10.3390/brainsci13091297.


Direct modulation index: A measure of phase amplitude coupling for neurophysiology data.

Scherer M, Wang T, Guggenberger R, Milosevic L, Gharabaghi A Hum Brain Mapp. 2022; 44(5):1862-1867.

PMID: 36579658 PMC: 9980882. DOI: 10.1002/hbm.26190.

References
1.
Tort A, Kramer M, Thorn C, Gibson D, Kubota Y, Graybiel A . Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task. Proc Natl Acad Sci U S A. 2008; 105(51):20517-22. PMC: 2629291. DOI: 10.1073/pnas.0810524105. View

2.
Fries P . A mechanism for cognitive dynamics: neuronal communication through neuronal coherence. Trends Cogn Sci. 2005; 9(10):474-80. DOI: 10.1016/j.tics.2005.08.011. View

3.
Siegel M, Donner T, Engel A . Spectral fingerprints of large-scale neuronal interactions. Nat Rev Neurosci. 2012; 13(2):121-34. DOI: 10.1038/nrn3137. View

4.
Gorgolewski K, Burns C, Madison C, Clark D, Halchenko Y, Waskom M . Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in python. Front Neuroinform. 2011; 5:13. PMC: 3159964. DOI: 10.3389/fninf.2011.00013. View

5.
Shaw J . Correlation and coherence analysis of the EEG: a selective tutorial review. Int J Psychophysiol. 1984; 1(3):255-66. DOI: 10.1016/0167-8760(84)90045-x. View