Bioavailability of Anthocyanins: Whole Foods Versus Extracts
Overview
Affiliations
Anthocyanins have gained significant popularity in recent years for their diverse health benefits, yet their limited bioavailability poses a challenge. To address this concern, technologies have emerged to enhance anthocyanin concentration, often isolating these compounds from other food constituents. However, the extent to which isolated anthocyanins confer health benefits compared to their whole-food counterparts remains unclear. This review explores the current literature on anthocyanin bioavailability and metabolism in the body, with a focus on comparing bioavailability when consumed as extracts versus whole foods rich in anthocyanins, drawing from in vitro, in vivo, and human clinical studies. While direct comparisons between anthocyanin bioavailability in whole foods versus isolates are scarce, prevailing evidence favours whole-food consumption over anthocyanin extracts. Further clinical investigations, preferably with direct comparisons, are needed to validate these findings and elucidate the nuanced interplay between anthocyanins and food matrices, informing future research directions and practical recommendations.
Reversing Glycation with a Dietary Supplement Containing Rosemary Extract.
Draelos Z, Bucay V, Watchmaker J, Valacchi G J Clin Aesthet Dermatol. 2025; 18(2):44-49.
PMID: 40078862 PMC: 11896625.
Biedermann L, Doulberis M, Schreiner P, Nielsen O, The F, Brand S Nutrients. 2024; 16(23.
PMID: 39683589 PMC: 11644667. DOI: 10.3390/nu16234197.
Poulios A, Papanikolaou K, Draganidis D, Tsimeas P, Chatzinikolaou A, Tsiokanos A Nutrients. 2024; 16(22).
PMID: 39599590 PMC: 11597853. DOI: 10.3390/nu16223803.
Senevirathna N, Hassanpour M, OHara I, Karim A Biomimetics (Basel). 2024; 9(11).
PMID: 39590274 PMC: 11592308. DOI: 10.3390/biomimetics9110702.
Galluzzi S, Marizzoni M, Gatti E, Bonfiglio N, Cattaneo A, Epifano F Nutr J. 2024; 23(1):135.
PMID: 39482712 PMC: 11529263. DOI: 10.1186/s12937-024-01039-8.