Puerarin-A Promising Flavonoid: Biosynthesis, Extraction Methods, Analytical Techniques, and Biological Effects

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2024 May 25

PMID 38791264

Authors

Sergio Liga

Cristina Paul

Affiliations

Soon will be listed here.

Abstract

Flavonoids, a variety of plant secondary metabolites, are known for their diverse biological activities. Isoflavones are a subgroup of flavonoids that have gained attention for their potential health benefits. Puerarin is one of the bioactive isoflavones found in the Kudzu root and genus, which is widely used in alternative Chinese medicine, and has been found to be effective in treating chronic conditions like cardiovascular diseases, liver diseases, gastric diseases, respiratory diseases, diabetes, Alzheimer's disease, and cancer. Puerarin has been extensively researched and used in both scientific and clinical studies over the past few years. The purpose of this review is to provide an up-to-date exploration of puerarin biosynthesis, the most common extraction methods, analytical techniques, and biological effects, which have the potential to provide a new perspective for medical and pharmaceutical research and development.

Citing Articles

Integrative Analyses of Metabolome and Transcriptome Reveal Regulatory Network of Puerarin Biosynthesis in var. .

Zhu T, He J, Li J, Liu C, Min X, Hu X Molecules. 2024; 29(23).

PMID: 39683717 PMC: 11643513. DOI: 10.3390/molecules29235556.

Green Synthesis of Zinc Oxide Nanoparticles Using Puerarin: Characterization, Antimicrobial Potential, Angiogenesis, and Safety Profile Assessment.

Liga S, Voda R, Lupa L, Paul C, Nemes N, Muntean D Pharmaceutics. 2024; 16(11).

PMID: 39598587 PMC: 11597859. DOI: 10.3390/pharmaceutics16111464.

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