Apatite-Forming Ability and Visible Light-Enhanced Antibacterial Activity of CuO-Supported TiO Formed on Titanium by Chemical and Thermal Treatments

Overview

Journal J Funct Biomater

Specialty Biomedical Engineering

Date 2024 May 24

PMID 38786626

Authors

Po-Cheng Sung

Taishi Yokoi

Masaya Shimabukuro

Takayuki Mokudai

Masakazu Kawashita

Affiliations

Soon will be listed here.

Abstract

Titanium with apatite-forming ability as well as antibacterial activity is useful as a component of antibacterial dental implants. When Ti was subjected to hydrogen peroxide (HO), copper acetate (Cu(OAc)), and heat (HO-Cu(OAc)-heat) treatments, a network structure of anatase and rutile titanium dioxide (TiO) and fine copper oxide (CuO) particles was formed on the Ti surface. The resulting samples accumulated a dense and uniform apatite layer on the surface when incubated in simulated body fluid and showed enhanced antibacterial activity against and under visible-light irradiation. Electron spin resonance spectra of HO-Cu(OAc)-heat-treated samples showed that hydroxyl radicals (·OH) were generated from the samples, and the concentration of ·OH increased with increasing Cu concentration of the Cu(OAc) solution. The enhanced antibacterial activity of these samples under visible-light irradiation may be attributable to the generation of ·OH from samples. These results suggest that Ti implants obtained using HO-Cu(OAc)-heat treatments and subjected to regular or on-demand visible-light irradiation may provide a decreased risk of peri-implantitis.

Citing Articles

Active Biomedical Materials and Their Applications.

Lung C J Funct Biomater. 2024; 15(9).

PMID: 39330226 PMC: 11433339. DOI: 10.3390/jfb15090250.

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