An E115A Missense Variant in CERS2 Is Associated With Increased Sleeping Energy Expenditure and Hepatic Insulin Resistance in American Indians
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
Article Highlights:
Citing Articles
Khan S, Ye W, Van J, Singh I, Rabiee Y, Rodricks K Sci Adv. 2025; 11(2):eadr1725.
PMID: 39792658 PMC: 11790001. DOI: 10.1126/sciadv.adr1725.
References
1.
Ravussin E, Lillioja S, Knowler W, Christin L, Freymond D, Abbott W
. Reduced rate of energy expenditure as a risk factor for body-weight gain. N Engl J Med. 1988; 318(8):467-72.
DOI: 10.1056/NEJM198802253180802.
View
2.
Summers S
. Could Ceramides Become the New Cholesterol?. Cell Metab. 2018; 27(2):276-280.
DOI: 10.1016/j.cmet.2017.12.003.
View
3.
Lillioja S, Mott D, Zawadzki J, Young A, Abbott W, Bogardus C
. Glucose storage is a major determinant of in vivo "insulin resistance" in subjects with normal glucose tolerance. J Clin Endocrinol Metab. 1986; 62(5):922-7.
DOI: 10.1210/jcem-62-5-922.
View
4.
Raichur S, Wang S, Chan P, Li Y, Ching J, Chaurasia B
. CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. Cell Metab. 2014; 20(4):687-95.
DOI: 10.1016/j.cmet.2014.09.015.
View
5.
Turpin-Nolan S, Bruning J
. The role of ceramides in metabolic disorders: when size and localization matters. Nat Rev Endocrinol. 2020; 16(4):224-233.
DOI: 10.1038/s41574-020-0320-5.
View