Deciphering the Progression of Fine-needle Aspiration: A Bibliometric Analysis of Thyroid Nodule Research

Overview

Journal Medicine (Baltimore)

Specialty General Medicine

Date 2024 May 17

PMID 38758913

Authors

Tengfei Liu

Fei Yang

Junli Qiao

Mengxuan Mao

Affiliations

Soon will be listed here.

Abstract

This study aims to dissect the evolution and pivotal shifts in Fine-Needle Aspiration (FNA) research for thyroid nodules over the past 2 decades, focusing on delineating key technological advancements and their impact on clinical practice. A comprehensive bibliometric analysis was conducted on 5418 publications from the Web of Science Core Collection database (2000-2023). Publications were rigorously selected based on their contributions to the advancement of FNA techniques and their influence on thyroid nodule management practices. Our analysis uncovered significant breakthroughs, most notably the incorporation of ultrasound and molecular diagnostics in FNA, which have markedly elevated diagnostic accuracy. A pivotal shift was identified towards minimally invasive post-FNA treatments, such as Radiofrequency Ablation, attributable to these diagnostic advancements. Additionally, the emergence of AI-assisted cytology represents a frontier in precision diagnostics, promising enhanced disease identification. The geographical analysis pinpointed the United States, Italy, and China as key contributors, with the United States leading in both publication volume and citation impact. This bibliometric analysis sheds light on the transformative progression in FNA practices for thyroid nodules, characterized by innovative diagnostic technologies and a trend towards patient-centric treatment approaches. The findings underscore the need for further research into AI integration and global practice standardization. Future explorations should focus on the practical application of these advancements in diverse healthcare settings and their implications for global thyroid nodule management.

References

Yang R, Zou X, Zeng H, Zhao Y, Ma X . Comparison of Diagnostic Performance of Five Different Ultrasound TI-RADS Classification Guidelines for Thyroid Nodules. Front Oncol. 2020; 10:598225. PMC: 7717965. DOI: 10.3389/fonc.2020.598225. View

Piticchio T, Russ G, Radzina M, Frasca F, Durante C, Trimboli P . Head-to-head comparison of American, European, and Asian TIRADSs in thyroid nodule assessment: systematic review and meta-analysis. Eur Thyroid J. 2024; 13(2). PMC: 10959032. DOI: 10.1530/ETJ-23-0242. View

Papini E, Monpeyssen H, Frasoldati A, Hegedus L . 2020 European Thyroid Association Clinical Practice Guideline for the Use of Image-Guided Ablation in Benign Thyroid Nodules. Eur Thyroid J. 2020; 9(4):172-185. PMC: 7445670. DOI: 10.1159/000508484. View

Orloff L, Noel J, Stack Jr B, Russell M, Angelos P, Baek J . Radiofrequency ablation and related ultrasound-guided ablation technologies for treatment of benign and malignant thyroid disease: An international multidisciplinary consensus statement of the American Head and Neck Society Endocrine Surgery Section.... Head Neck. 2021; 44(3):633-660. DOI: 10.1002/hed.26960. View

Kim E, Park C, Chung W, Oh K, Kim D, Lee J . New sonographic criteria for recommending fine-needle aspiration biopsy of nonpalpable solid nodules of the thyroid. AJR Am J Roentgenol. 2002; 178(3):687-91. DOI: 10.2214/ajr.178.3.1780687. View

Alshoabi S, Binnuhaid A . Diagnostic accuracy of ultrasonography versus fine-needle-aspiration cytology for predicting benign thyroid lesions. Pak J Med Sci. 2019; 35(3):630-635. PMC: 6572947. DOI: 10.12669/pjms.35.3.292. View

Cibas E, Ali S . The Bethesda System for Reporting Thyroid Cytopathology. Thyroid. 2009; 19(11):1159-65. DOI: 10.1089/thy.2009.0274. View

Holt E . Current Evaluation of Thyroid Nodules. Med Clin North Am. 2021; 105(6):1017-1031. DOI: 10.1016/j.mcna.2021.06.006. View

Gharib H, Papini E, Garber J, Duick D, Harrell R, Hegedus L . AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ASSOCIAZIONE MEDICI ENDOCRINOLOGI MEDICAL GUIDELINES FOR CLINICAL PRACTICE FOR THE DIAGNOSIS AND MANAGEMENT OF THYROID NODULES--2016 UPDATE. Endocr Pract. 2016; 22(5):622-39. DOI: 10.4158/EP161208.GL. View

10.

Radzina M, Cantisani V, Rauda M, Nielsen M, Ewertsen C, DAmbrosio F . Update on the role of ultrasound guided radiofrequency ablation for thyroid nodule treatment. Int J Surg. 2017; 41 Suppl 1:S82-S93. DOI: 10.1016/j.ijsu.2017.02.010. View

11.

Sharma P, Hu-Lieskovan S, Wargo J, Ribas A . Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy. Cell. 2017; 168(4):707-723. PMC: 5391692. DOI: 10.1016/j.cell.2017.01.017. View

12.

Chiosea S, Hodak S, Yip L, Abraham D, Baldwin C, Baloch Z . Molecular Profiling of 50 734 Bethesda III-VI Thyroid Nodules by ThyroSeq v3: Implications for Personalized Management. J Clin Endocrinol Metab. 2023; 108(11):2999-3008. PMC: 10583990. DOI: 10.1210/clinem/dgad220. View

13.

Alexander E, Cibas E . Diagnosis of thyroid nodules. Lancet Diabetes Endocrinol. 2022; 10(7):533-539. DOI: 10.1016/S2213-8587(22)00101-2. View

14.

Rajab M, Payne R, Forest V, Pusztaszeri M . Molecular Testing for Thyroid Nodules: The Experience at McGill University Teaching Hospitals in Canada. Cancers (Basel). 2022; 14(17). PMC: 9454567. DOI: 10.3390/cancers14174140. View

15.

Steward D, Carty S, Sippel R, Yang S, Sosa J, Sipos J . Performance of a Multigene Genomic Classifier in Thyroid Nodules With Indeterminate Cytology: A Prospective Blinded Multicenter Study. JAMA Oncol. 2018; 5(2):204-212. PMC: 6439562. DOI: 10.1001/jamaoncol.2018.4616. View

16.

Akgun E, Romero-Velez G, Berber E . Assessing the efficacy of thyroid nodule radiofrequency ablation using patient-reported outcome measures. Surgery. 2023; 175(3):654-660. DOI: 10.1016/j.surg.2023.07.032. View

17.

Alexander E, Kennedy G, Baloch Z, Cibas E, Chudova D, Diggans J . Preoperative diagnosis of benign thyroid nodules with indeterminate cytology. N Engl J Med. 2012; 367(8):705-15. DOI: 10.1056/NEJMoa1203208. View

18.

Hegedus L . Clinical practice. The thyroid nodule. N Engl J Med. 2004; 351(17):1764-71. DOI: 10.1056/NEJMcp031436. View

19.

Valabrega S, Santolamazza G, Romanelli F, Scapicchio G, DAngelo F, Bellotti C . Cancer Rate of the Indeterminate Lesions at Low or High Risk According to Italian System for Reporting of Thyroid FNA. Front Endocrinol (Lausanne). 2018; 9:371. PMC: 6052905. DOI: 10.3389/fendo.2018.00371. View

20.

Kobaly K, Kim C, Mandel S . Contemporary Management of Thyroid Nodules. Annu Rev Med. 2021; 73:517-528. DOI: 10.1146/annurev-med-042220-015032. View