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Under Pressure - A Historical Vignette on Surgical Timing in Traumatic Spinal Cord Injury

Overview
Journal Brain Spine
Specialty Neurology
Date 2024 May 17
PMID 38756860
Authors
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Abstract

Introduction: It was not even a century ago when a spinal cord injury (SCI) would inevitably result in a fatal outcome, particularly for those with complete SCI. Throughout history, there have been extensive endeavours to change the prospects for SCI patients by performing surgery, even though many believed that there was no way to alter the catastrophic course of SCI. To this day, the debate regarding the efficacy of surgery in improving the neurological outcome for SCI patients persists, along with discussions about the timing of surgical intervention.

Research Question: How have the historical surgical results shaped our perspective on the surgical treatment of SCI?

Material And Methods: Narrative literature review.

Results: Throughout history there have been multiple surgical attempts to alter the course of SCI, with conflicting results. While studies suggest a potential link between timing of surgery and neurological recovery, the exact impact of immediate surgery on individual cases remains ambiguous. It is becoming more evident that, alongside surgical intervention, factors specific to both the patient and their surgical treatment will significantly influence neurological recovery.

Conclusion: Although a growing number of studies indicates a potential correlation of surgical timing and neurological outcome, the precise influence of urgent surgery on an individual basis remains uncertain. It is increasingly apparent that, despite surgery, patient- and treatment-specific factors will also play a role in determining the neurological outcome. Notably, these very factors have influenced the results in previous studies and our views concerning surgical timing.

Citing Articles

The concepts of Intra Spinal Pressure (ISP), Intra Thecal Pressure (ITP), and Spinal Cord Perfusion Pressure (SCPP) in acute, severe traumatic spinal cord injury: Narrative review.

Saadoun S, Asif H, Papadopoulos M Brain Spine. 2024; 4:103919.

PMID: 39654909 PMC: 11626061. DOI: 10.1016/j.bas.2024.103919.

References
1.
. II. Thorburn on the Surgery of the Spinal Cord and Its Appendages. Ann Surg. 1894; 20(4):454-69. PMC: 1493866. DOI: 10.1097/00000658-189407000-00057. View

2.
. Lectures on the Diagnosis and Treatment of the Principal Forms of Paralysis of the Lower Extremities. Br Foreign Med Chir Rev. 2018; 29(58):371-412. PMC: 5182310. View

3.
Bodner D . A pioneer in optimism: the legacy of Donald Munro, MD. J Spinal Cord Med. 2009; 32(4):355-6. PMC: 2830672. DOI: 10.1080/10790268.2009.11754510. View

4.
Rahimi-Movaghar V, Niakan A, Haghnegahdar A, Shahlaee A, Saadat S, Barzideh E . Early versus late surgical decompression for traumatic thoracic/thoracolumbar (T1-L1) spinal cord injured patients. Primary results of a randomized controlled trial at one year follow-up. Neurosciences (Riyadh). 2014; 19(3):183-91. PMC: 4727651. View

5.
Biglari B, Child C, Yildirim T, Swing T, Reitzel T, Moghaddam A . Does surgical treatment within 4 hours after trauma have an influence on neurological remission in patients with acute spinal cord injury?. Ther Clin Risk Manag. 2016; 12:1339-46. PMC: 5012849. DOI: 10.2147/TCRM.S108856. View