Bilateral Renal Cell Carcinoma in the Horseshoe Kidney With Metastasis in Gallbladder, Pancreas and Duodenum: A Report of a Rare Case and Literature Review

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2024 May 17

PMID 38756314

Authors

Chetana Ratnaparkhi

Avinash Dhok

Neeraj Kumar

Shantanu Pande

Sakshi Jeswani

Affiliations

Soon will be listed here.

Abstract

Horseshoe kidney is the most common renal fusion anomaly and is associated with various complications, ranging from infections to neoplasms. While renal cell carcinoma (RCC) is the most frequent renal neoplasm in adults, its occurrence in a horseshoe kidney is rare, and bilateral involvement is rarer. Furthermore, RCC metastasizing to organs is known and rare sites of metastasis are also documented. The report presents a unique case of bilateral RCC in a horseshoe kidney with synchronous metastasis to the gallbladder, pancreas, and duodenum. This presentation, involving metastasis to these specific organs, is exceedingly uncommon, making it a rarest of rare possibilities. The current case report underscores the importance of vigilant monitoring and comprehensive evaluation in patients with horseshoe kidneys, as they may be predisposed to unusual complications like RCC and rare site metastasis.

References

Kim T . Renal cell carcinoma in a horseshoe kidney and preoperative superselective renal artery embolization: a case report. Korean J Radiol. 2005; 6(3):200-3. PMC: 2685045. DOI: 10.3348/kjr.2005.6.3.200. View

Sheth S, Scatarige J, Horton K, Corl F, Fishman E . Current concepts in the diagnosis and management of renal cell carcinoma: role of multidetector ct and three-dimensional CT. Radiographics. 2001; 21 Spec No:S237-54. DOI: 10.1148/radiographics.21.suppl_1.g01oc18s237. View

Oliva M, Glickman J, Zou K, Teo S, Mortele K, Rocha M . Renal cell carcinoma: t1 and t2 signal intensity characteristics of papillary and clear cell types correlated with pathology. AJR Am J Roentgenol. 2009; 192(6):1524-30. DOI: 10.2214/AJR.08.1727. View

Janzen N, Kim H, Figlin R, Belldegrun A . Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease. Urol Clin North Am. 2003; 30(4):843-52. DOI: 10.1016/s0094-0143(03)00056-9. View

Jones L, Reeves M, Wingo S, Babanoury A . Malignant tumor in a horseshoe kidney. Urol J. 2007; 4(1):46-8. View

Minni F, Casadei R, Perenze B, Greco V, Marrano N, Margiotta A . Pancreatic metastases: observations of three cases and review of the literature. Pancreatology. 2004; 4(6):509-20. DOI: 10.1159/000080248. View

Adsay N, Andea A, Basturk O, Kilinc N, Nassar H, Cheng J . Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature. Virchows Arch. 2004; 444(6):527-35. DOI: 10.1007/s00428-004-0987-3. View

Mirzazadeh M, Richards K . Complete duplication of collecting system in a horseshoe kidney presenting with recurrent urinary tract infections: report of an exceedingly rare congenital anomaly and review of literature. ScientificWorldJournal. 2012; 11:1591-6. PMC: 3201630. DOI: 10.1100/tsw.2011.143. View

Ljungberg B, Bensalah K, Canfield S, Dabestani S, Hofmann F, Hora M . EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol. 2015; 67(5):913-24. DOI: 10.1016/j.eururo.2015.01.005. View

10.

Costa Neves M, Neofytou K, Giakoustidis A, Hazell S, Wotherspoon A, Gore M . Two cases of gallbladder metastasis from renal cell carcinoma and review of literature. World J Surg Oncol. 2016; 14:87. PMC: 4802731. DOI: 10.1186/s12957-016-0843-3. View