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Management of Hypertension Addressing Hyperuricaemia: Introduction of Nano-based Approaches

Overview
Journal Ann Med
Publisher Informa Healthcare
Specialty General Medicine
Date 2024 May 16
PMID 38753584
Authors
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Abstract

Uric acid (UA) levels in blood serum have been associated with hypertension, indicating a potential causal relationship between high serum UA levels and the progression of hypertension. Therefore, the reduction of serum UA level is considered a potential strategy for lowering and mitigating blood pressure. If an individual is at risk of developing or already manifesting elevated blood pressure, this intervention could be an integral part of a comprehensive treatment plan. By addressing hyperuricaemia, practitioners may subsidize the optimization of blood pressure regulation, which illustrates the importance of addressing UA levels as a valuable strategy within the broader context of hypertension management. In this analysis, we outlined the operational principles of effective xanthine oxidase inhibitors for the treatment of hyperuricaemia and hypertension, along with an exploration of the contribution of nanotechnology to this field.

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Causal impact of human blood metabolites and metabolic pathways on serum uric acid and gout: a mendelian randomization study.

Zhong Y, Yang C, Zhang B, Chen Y, Cai W, Wang G Front Endocrinol (Lausanne). 2024; 15:1378645.

PMID: 39027467 PMC: 11256090. DOI: 10.3389/fendo.2024.1378645.

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