VLP-based Model for the Study of Airborne Viral Pathogens

Overview

Journal Microbiol Spectr

Specialty Microbiology

Date 2024 May 16

PMID 38752752

Authors

Michael Caffrey

Nitin Jayakumar

Veronique Caffrey

Varada Anirudhan

Lijun Rong

Igor Paprotny

Affiliations

Soon will be listed here.

Abstract

Importance: The study and detection of airborne pathogens are hampered by the lack of appropriate model systems. In this work, we demonstrate that noninfectious virus-like particles (VLPs) represent attractive models to study airborne viral pathogens. Specifically, VLPs are readily prepared, are similar in size and composition to infectious viruses, and are amenable to highly sensitive nucleic acid amplification techniques.

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