Distal Margin Distance in Radical Resection of Locally Advanced Rectal Cancer After Neoadjuvant Therapy

Overview

Journal Chin J Cancer Res

Specialty Oncology

Date 2024 May 16

PMID 38751434

Authors

Jun Luo

Mingxuan Zhu

Long Zhao

Meiwen He

Bei Li

Yifan Liu

Yuhan Sun

Guoqing Lyu

Zhanlong Shen

Affiliations

Soon will be listed here.

Abstract

Colorectal cancer has a high incidence and mortality rate in China, with the majority of cases being middle and low rectal cancer. Surgical intervention is currently the main treatment modality for locally advanced rectal cancer, with the common goal of improving oncological outcomes while preserving function. The controversy regarding the circumferential resection margin distance in rectal cancer surgery has been resolved. With the promotion of neoadjuvant therapy concepts and advancements in technology, treatment strategies have become more diverse. Following tumor downstaging, there is an increasing trend towards extending the safe distance of distal rectal margin. This provides more opportunities for patients with low rectal cancer to preserve their anal function. However, there is currently no consensus on the specific distance of distal resection margin.

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