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Propelling Gold Nanozymes: Catalytic Activity and Biosensing Applications

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Specialty Chemistry
Date 2024 May 15
PMID 38748246
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Abstract

Recently, gold nanomaterials have been rapidly developed owing to their high stability, good biocompatibility, and multifunctionality. The unique catalytic activity of gold nanomaterials has driven the emergence of the concept for a "gold nanozyme." Understanding the characteristics of gold nanozymes is crucial for improving their catalytic performance as well as expanding their applications. In this review, we provide an overview of the intrinsic enzyme-like activities of gold nanozymes, including peroxidase-, catalase-, superoxide dismutase-, and glucose oxidase-like activities, and the catalytic mechanisms involved. In addition, strategies for modulating the catalytic activity of gold nanozymes and their applications in biosensing were discussed in detail. Moreover, we highlight the current challenges of gold nanozymes and look forward to attracting more attention for propelling the developments in this field.

References
1.
Huang Y, Ren J, Qu X . Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications. Chem Rev. 2019; 119(6):4357-4412. DOI: 10.1021/acs.chemrev.8b00672. View

2.
Wu J, Wang X, Wang Q, Lou Z, Li S, Zhu Y . Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II). Chem Soc Rev. 2018; 48(4):1004-1076. DOI: 10.1039/c8cs00457a. View

3.
Lin Y, Ren J, Qu X . Nano-gold as artificial enzymes: hidden talents. Adv Mater. 2014; 26(25):4200-17. DOI: 10.1002/adma.201400238. View

4.
Ma Y, Tian Z, Zhai W, Qu Y . Insights on catalytic mechanism of CeO as multiple nanozymes. Nano Res. 2022; 15(12):10328-10342. PMC: 9274632. DOI: 10.1007/s12274-022-4666-y. View

5.
Wang N, Dong T, Shi W, Li L, Ye M, Fu X . Carbon dot decorated CoO nanozymes responsive to the NIR-II window for mild photothermal-enhanced nanocatalytic therapy. J Mater Chem B. 2023; 11(27):6372-6382. DOI: 10.1039/d3tb00254c. View