Physicochemical Parameters Affecting the Adhesion of Ciprofloxacin-resistant to Activated Sludge

Overview

Journal Water Sci Technol

Specialties Environmental Health
Toxicology

Date 2024 May 15

PMID 38747960

Authors

Yuki Nakaya

Natsumi Nagahashi

Reiko Hirano

Yusuke Ishizuka

Hisashi Satoh

Affiliations

Soon will be listed here.

Abstract

To investigate the physicochemical conditions necessary to stably remove antibiotic-resistant bacteria (ARB) via contact with activated sludge (AS), the adhesion of ciprofloxacin (CIP)-resistant and -susceptible to AS was simulated by contact tests in the laboratory. The CIP-resistant and susceptible were removed by a 3 log smaller concentration by a 5 h contact test at maximum. Considering the hydraulic retention time of a reaction tank (∼5 h) and step-feeding operation, we considered the removal rate of in the current simulated contact test to be in agreement with the actual situation where 1-2 log concentrations of were reported to be removed from an AS reaction tank. With the increase in the AS concentration and/or dissolved oxygen, the removal rate of increased. The removal rate of CIP-resistant was greater than that of susceptible under all experimental conditions. Although the mechanism by which CIP-resistant preferably adhered to AS was not clearly understood in detail, finding optimum conditions under which bacteria, including ARB, were efficiently removed by the AS process may be possible

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