Patient-, Implant- and Prosthetic-related Factors on Peri-implant Mucositis and Bone Loss

Overview

Journal Braz Oral Res

Specialty Dentistry

Date 2024 May 15

PMID 38747827

Authors

Lelis Gustavo Nicoli

Carolina Mendonca de Almeida Malzoni

Paulo Fermino da Costa Neto

Claudio Marcantonio

Suzane Cristina Pigossi

Cassiano Kuchenbecker Rosing

Francisco Wilker Mustafa Gomes Muniz

Marcelo Goncalves

Daniela Leal Zandim-Barcelos

Elcio Marcantonio Junior

Affiliations

Soon will be listed here.

Abstract

Peri-implant diseases, including peri-implant mucositis (PIM) and peri-implantitis, are a chronic inflammatory disorder triggered by bacterial biofilm in susceptible hosts. Potential risk factors for peri-implant diseases include smoking, dental plaque accumulation, poor oral hygiene, genetics, and absence of peri-implant keratinized mucosa. This cohort study aimed to evaluate the influence of patient-, implant-, and prosthetic-related factors on PIM and peri-implant bone loss (PBL) around dental implants after 1 year of loading. A total of 54 subjects (22 males and 32 females) were included in the study. Peri-implant clinical parameters were assessed and standardized periapical radiographs of each dental implant were obtained 15 days after the definitive prosthesis installation (baseline) and at 3, 6, and 12 months of follow-up. A total of 173 implants were evaluated. PIM affected 44.8% of the implants and no significant association was found between the investigated parameters and PIM incidence, except for type of implant connection. A significantly higher incidence of PIM (80.0%) was observed for implants with internal hexagon connection type after 1 year of follow-up (p = 0.015). Moreover, a mean PBL of 0.35 ± 1.89 mm was observed and no dental implant was affected by peri-implantitis after 1 year of function. No specific influence of patient, implant, or prosthetic factors on PBL was observed. No association was found between the occurrence of PIM/PBL and the patient-, implant-, and prosthetic-related factors investigated in this cohort study, except for the type of dental-implant connection.

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References

Ferreira S, Silva G, Cortelli J, Costa J, Costa F . Prevalence and risk variables for peri-implant disease in Brazilian subjects. J Clin Periodontol. 2006; 33(12):929-35. DOI: 10.1111/j.1600-051X.2006.01001.x. View

Nickenig H, Wichmann M, Schlegel K, Nkenke E, Eitner S . Radiographic evaluation of marginal bone levels adjacent to parallel-screw cylinder machined-neck implants and rough-surfaced microthreaded implants using digitized panoramic radiographs. Clin Oral Implants Res. 2009; 20(6):550-4. DOI: 10.1111/j.1600-0501.2008.01684.x. View

Poli P, Beretta M, Grossi G, Maiorana C . Risk indicators related to peri-implant disease: an observational retrospective cohort study. J Periodontal Implant Sci. 2016; 46(4):266-76. PMC: 5005814. DOI: 10.5051/jpis.2016.46.4.266. View

Lemos C, Verri F, Bonfante E, Ferreira Santiago Junior J, Pellizzer E . Comparison of external and internal implant-abutment connections for implant supported prostheses. A systematic review and meta-analysis. J Dent. 2017; 70:14-22. DOI: 10.1016/j.jdent.2017.12.001. View

Lang N, Berglundh T . Periimplant diseases: where are we now?--Consensus of the Seventh European Workshop on Periodontology. J Clin Periodontol. 2011; 38 Suppl 11:178-81. DOI: 10.1111/j.1600-051X.2010.01674.x. View

Mei D, Zhao B, Xu H, Wang Y . Radiographic and clinical outcomes of rooted, platform-switched, microthreaded implants with a sandblasted, large-grid, and acid-etched surface: A 5-year prospective study. Clin Implant Dent Relat Res. 2017; 19(6):1074-1081. DOI: 10.1111/cid.12543. View

Fransson C, Tomasi C, Pikner S, Grondahl K, Wennstrom J, Leyland A . Severity and pattern of peri-implantitis-associated bone loss. J Clin Periodontol. 2010; 37(5):442-8. DOI: 10.1111/j.1600-051X.2010.01537.x. View

Lee C, Huang Y, Zhu L, Weltman R . Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis. J Dent. 2017; 62:1-12. DOI: 10.1016/j.jdent.2017.04.011. View

Scarano A, Lorusso C, Di Giulio C, Mazzatenta A . Evaluation of the Sealing Capability of the Implant Healing Screw by Using Real Time Volatile Organic Compounds Analysis: Internal Hexagon Versus Cone Morse. J Periodontol. 2016; 87(12):1492-1498. DOI: 10.1902/jop.2016.160076. View

10.

de Brandao M, Vettore M, Vidigal Junior G . Peri-implant bone loss in cement- and screw-retained prostheses: systematic review and meta-analysis. J Clin Periodontol. 2013; 40(3):287-95. DOI: 10.1111/jcpe.12041. View

11.

AlJasser R, AlSarhan M, Alotaibi D, Aloraini S, Ansari A, Habib S . Analysis of Prosthetic Factors Affecting Peri-Implant Health: An in vivo Retrospective Study. J Multidiscip Healthc. 2021; 14:1183-1191. PMC: 8164962. DOI: 10.2147/JMDH.S312926. View

12.

Nickenig H, Wichmann M, Schlegel K, Nkenke E, Eitner S . Radiographic evaluation of marginal bone levels during healing period, adjacent to parallel-screw cylinder implants inserted in the posterior zone of the jaws, placed with flapless surgery. Clin Oral Implants Res. 2010; 21(12):1386-93. DOI: 10.1111/j.1600-0501.2010.01961.x. View

13.

Cox J, Zarb G . The longitudinal clinical efficacy of osseointegrated dental implants: a 3-year report. Int J Oral Maxillofac Implants. 1987; 2(2):91-100. View

14.

Lopez N, Smith P, Gutierrez J . Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: a randomized controlled trial. J Periodontol. 2002; 73(8):911-24. DOI: 10.1902/jop.2002.73.8.911. View

15.

Lindhe J, Berglundh T, Ericsson I, Liljenberg B, Marinello C . Experimental breakdown of peri-implant and periodontal tissues. A study in the beagle dog. Clin Oral Implants Res. 1992; 3(1):9-16. DOI: 10.1034/j.1600-0501.1992.030102.x. View

16.

Kim B, Kim Y, Yun P, Yi Y, Lee H, Kim S . Evaluation of peri-implant tissue response according to the presence of keratinized mucosa. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 107(3):e24-8. DOI: 10.1016/j.tripleo.2008.12.010. View

17.

Muniz F, Montagner F, Jacinto R, Rosing C, Gomes B . Correlation between crestal alveolar bone loss with intracanal bacteria and apical lesion area in necrotic teeth. Arch Oral Biol. 2018; 95:1-6. DOI: 10.1016/j.archoralbio.2018.07.007. View

18.

Rodrigo D, Martin C, Sanz M . Biological complications and peri-implant clinical and radiographic changes at immediately placed dental implants. A prospective 5-year cohort study. Clin Oral Implants Res. 2011; 23(10):1224-31. DOI: 10.1111/j.1600-0501.2011.02294.x. View

19.

Castro D, Araujo M, Benfatti C, Araujo C, Piattelli A, Perrotti V . Comparative histological and histomorphometrical evaluation of marginal bone resorption around external hexagon and Morse cone implants: an experimental study in dogs. Implant Dent. 2014; 23(3):270-6. DOI: 10.1097/ID.0000000000000089. View

20.

Linkevicius T, Puisys A, Vindasiute E, Linkeviciene L, Apse P . Does residual cement around implant-supported restorations cause peri-implant disease? A retrospective case analysis. Clin Oral Implants Res. 2012; 24(11):1179-84. DOI: 10.1111/j.1600-0501.2012.02570.x. View