The Times Are Changing: A Primer on Novel Clinical Trial Designs and Endpoints in Critical Care Research
Overview
Overview
Journal
Am J Health Syst Pharm
Publisher
Oxford University Press
Specialties
Health Services
Pharmacology
Pharmacy
Pharmacology
Pharmacy
Date
2024 May 14
PMID
38742701
Authors
Affiliations
Affiliations
Soon will be listed here.
References
1.
Keinath J, Lekura J, Hauser C, Bajwa M, Bloome M, Kalus J
. Deterioration free discharge comparison of andexanet-alfa and prothrombin complex concentrates (PCC) for reversal of factor Xa inhibitor associated bleeds. J Thromb Thrombolysis. 2023; 56(2):315-322.
DOI: 10.1007/s11239-023-02840-8.
View
2.
Vincent J, Opal S, Marshall J
. Ten reasons why we should NOT use severity scores as entry criteria for clinical trials or in our treatment decisions. Crit Care Med. 2009; 38(1):283-7.
DOI: 10.1097/CCM.0b013e3181b785a2.
View
3.
Langley R, Tsalik E, van Velkinburgh J, Glickman S, Rice B, Wang C
. An integrated clinico-metabolomic model improves prediction of death in sepsis. Sci Transl Med. 2013; 5(195):195ra95.
PMC: 3924586.
DOI: 10.1126/scitranslmed.3005893.
View
4.
Bollaert P, Monnier A, Schneider F, Argaud L, Badie J, Charpentier C
. Fluid balance control in critically ill patients: results from POINCARE-2 stepped wedge cluster-randomized trial. Crit Care. 2023; 27(1):66.
PMC: 9945675.
DOI: 10.1186/s13054-023-04357-1.
View
5.
Kumar A, Roberts D, Wood K, Light B, Parrillo J, Sharma S
. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006; 34(6):1589-96.
DOI: 10.1097/01.CCM.0000217961.75225.E9.
View